Pathophysiology of hepatic insufficiency
- Authors: Brus T.V.1, Evgrafov V.A.1
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Affiliations:
- St. Petersburg State Pediatric Medical University
- Issue: Vol 13, No 3 (2022)
- Pages: 55-64
- Section: Lecture
- URL: https://journals.rcsi.science/pediatr/article/view/109759
- DOI: https://doi.org/10.17816/PED13355-64
- ID: 109759
Cite item
Abstract
The liver is a unique and complex functioning organ, which is central in the metabolism of proteins, carbohydrates, fats and plays an important role in digestion, hematopoiesis, hemocoagulation, and detoxification processes. The pathology of the liver is complex and diverse, often accompanied by the pathology of other organs. Liver diseases are often encountered by doctors of various specialties, and for the clinician, knowledge of this pathology of this organ is essential. Currently, there is a steady increase in the number of patients with liver diseases, mostly people of working age. The development of acute and chronic liver pathology in the vast majority of cases is accompanied by the occurrence of various complications, up to the appearance of liver failure.
The lecture contains up-to-date information about the etiology and pathogenesis of hepatic pathology. Pathological processes in the liver are considered taking into account the complexity of its structural and functional organization. The main symptoms and syndromes of liver pathology are described, their pathophysiological assessment is given. Modern classifications of jaundice, hepatitis, liver failurea regiven.
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##article.viewOnOriginalSite##About the authors
Tatyana V. Brus
St. Petersburg State Pediatric Medical University
Author for correspondence.
Email: bant.90@mail.ru
PhD, MD, Associate Professor of the Department of Pathological Physiology with a Class of Immunopathology
Russian Federation, Saint PetersburgVladimir A. Evgrafov
St. Petersburg State Pediatric Medical University
Email: psh_k@mail.ru
PhD, MD, Associate Professor of the Department, of Anesthesiology, Resuscitation and Emergency Pediatrics
Russian Federation, Saint PetersburgReferences
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