Acute thymic hemorrhage, simulating an anterior mediastinal mass, as a complication of hemorrhagic disease of the newborn
- Authors: Podkamenev A.V.1, Karavaeva S.A.2, Mysnikova I.V.1, Syrtsova A.R.1, Ti R.A.1, Pozdnyakova O.F.1, Kondratiev G.V.1, Kupatadze D.D.1, Lee A.G.1, Nazarova I.V.1
-
Affiliations:
- St. Petersburg State Pediatric Medical University
- North-Western State Medical University named after I.I. Mechnikov
- Issue: Vol 9, No 5 (2018)
- Pages: 120-124
- Section: Articles
- URL: https://journals.rcsi.science/pediatr/article/view/10826
- DOI: https://doi.org/10.17816/PED95120-124
- ID: 10826
Cite item
Full Text
Abstract
Mediastinum is one of the most frequent localizations of pathological mass in childhood. In most cases, mediastinal masses require surgical treatment or biopsy. Spontaneous acute thymic hemorrhage, as a complication of hemorrhagic disease of newborn, is an extremely rare condition with life-threatening clinical manifestations. In patients with such disease radiological findings may be mistakenly regarded as tumor, and lead to aggressive surgical treatment. We report a case of a newborn with a late-onset form of hemorrhagic disease, complicated by thymic hemorrhage, simulating an anterior mediastinal mass.
Full Text
##article.viewOnOriginalSite##About the authors
Alexey V. Podkamenev
St. Petersburg State Pediatric Medical University
Author for correspondence.
Email: podkamenev@hotmail.com
MD, Assistant Professor of the Department of Surgical Diseases of Children’s Age
Russian Federation, Saint PetersburgSvetlana A. Karavaeva
North-Western State Medical University named after I.I. Mechnikov
Email: swetl.karawaewa2015@yandex.ru
Professor, PhD, Head of the Pediatric Surgery Department
Russian Federation, Saint PetersburgIrina V. Mysnikova
St. Petersburg State Pediatric Medical University
Email: irinayurko2014@yandex.ru
Neonatologist, Head of the Department of Pathology of Newborns and Infants, Perinatal Center Clinic
Russian Federation, Saint PetersburgArina R. Syrtsova
St. Petersburg State Pediatric Medical University
Email: syrcovaarina@gmail.com
Pediatric Surgeon, Department of Pathology of Newborns and Infants, Perinatal Center Clinic
Russian Federation, Saint PetersburgRoman A. Ti
St. Petersburg State Pediatric Medical University
Email: sprut009@yandex.ru
Pediatric Surgeon, Department of Pathology of Newborns and Infants, Perinatal Center Clinic
Russian Federation, Saint PetersburgOlga F. Pozdnyakova
St. Petersburg State Pediatric Medical University
Email: Goodmedic@yandex.ru
MD, PhD, Radiologist, Radiology Department
Russian Federation, Saint PetersburgGleb V. Kondratiev
St. Petersburg State Pediatric Medical University
Email: spbgvk@mail.ru
Pediatric Oncologist, Assistant and Head of Education of the Department of Oncology, Pediatric Oncology with a Course of Radiation Oncology Diagnostics and Radiotherapy
Russian Federation, Saint PetersburgDmitry D. Kupatadze
St. Petersburg State Pediatric Medical University
Email: ddkupatadze@gmail.com
MD, Professor, Head of the Department of Surgical Diseases of Children’s Age
Russian Federation, Saint PetersburgAlexandr G. Lee
St. Petersburg State Pediatric Medical University
Email: alee1972@mail.ru
Head of Department of Reanimation and Intensive Care of Newborns, Perinatal Center Clinic
Russian Federation, Saint PetersburgInna V. Nazarova
St. Petersburg State Pediatric Medical University
Email: inesfedja@mail.ru
Anesthesiologist and Intensive Care Specialist, Department of Reanimation and Intensive Therapy of Newborns, Perinatal Center Clinic
Russian Federation, Saint PetersburgReferences
- Белогурова М.Б. Детская онкология. Руководство для врачей. - СПб.: СпецЛит, 2002. [Belogurova MB. Detskaya onkologiya. Rukovodstvo dlya vrachey. Saint Petersburg: SpetsLit; 2002. (In Russ.)]
- Шабалов Н.П. Неонатология. Т. 2. - М.: МЕДпресс-информ, 2004. [Shabalov NP. Neonatologiya. Vol. 2. Moscow: MEDpress-inform; 2004. (In Russ.)]
- Gargano G, Paltrinieri AL, Gallo C, et al. Massive thymic hemorrhage and hemothorax occurring in utero. Ital J Pediatr. 2015;41:88. doi: 10.1186/s13052-015-0196-5.
- Palau MA, Winters A, Liang X, et al. Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature. Case Rep Pediatr. 2017;2017:7628946. doi: 10.1155/2017/7628946.
- Bees NR, Richards SW, Fearne C, et al. Neonatal thymic haemorrhage. Br J Radiol. 1997;70:210-212. doi: 10.1259/bjr.70.830.9135451.
- Urvoas E, Pariente D, Rousset A, et al. Ultrasound diagnosis of thymic hemorrhage in an infant with late-onset hemorrhagic disease. Pediatr Radiol. 1994;24(2):96-97. doi: 10.1007/bf02020161.
- Lemaitre L, Leclerc F, Dubos JP, et al. Thymic hemorrhage: a cause of acute symptomatic mediastinal widening in an infant with late haemorrhagic disease. Pediatr Radiol. 1989;19(2):128-129. doi: 10.1007/bf02387903.
- Woolley MM, Isaacs H, Lindesmith G, et al. Spontaneous thymic hemorrhage in the neonate: Report of two cases. J Pediatr Surg. 1974;9(2):231-233. doi: 10.1016/s0022-3468(74)80128-4.
- Day DL, Gedgaudas E. Symposium on Nonpulmonary Aspects in Chest Radiology. The thymus. Radiol Clin North Am. 1984;22(3):519-538.
- Han BK, Babcock DS, Oestreich AE. Normal thymus in infancy: sonographic characteristics. Radiology. 1989;170(2):471-474. doi: 10.1148/radiology.170.2.2643142.
Supplementary files
