Is psoriasis therapy an art based on experience?
- Authors: Zaslavsky D.V.1, Chuprov I.N.2, Nasyrov R.A.1, Krasnogorskaya O.L.1, Bolshakova E.S.1, Manylova E.S.1, Mineeva O.K.1, Drozdova L.N.1, Shternliht K.V.1, Sidikov A.A.3, Kovalenko K.A.1, Brazhnikova A.P.1, Kozlova D.V.1
-
Affiliations:
- St. Petersburg State Pediatric Medical University
- St. Petersburg State North-Western Medical University named after I.I. Mechnikov
- Fergana Medical Institute of Public Health
- Issue: Vol 12, No 6 (2021)
- Pages: 77-88
- Section: Reviews
- URL: https://journals.rcsi.science/pediatr/article/view/106326
- DOI: https://doi.org/10.17816/PED12677-88
- ID: 106326
Cite item
Abstract
Psoriasis is a chronic immune-associated skin disease of a multifactorial nature with phenotypic diversity in the general population, as well as a large number of comorbid diseases in patients. The generalized pustular psoriasis, historically was considered one of the variants of the course of psoriasis. Today some authors classify it as a genetically different condition combined with a plaque psoriasis. The selected tactics of psoriasis therapy can become a trigger for the manifestation of a pustular form. Despite the availability of modern data on the immunopathogenesis of the disease, there are no standardized methods of treatment that can take into account the individual characteristics of patients, which is doubly important in pediatric practice, since the arsenal of drugs approved for use is limited. We demonstrate the clinical case of a patient with progressive plaque psoriasis, earlier getting systemic and topical corticosteroids for a long time. This therapy did not allowed to take the course of the disease under control, even more it caused appearance of complications. Our clinical example from practice allows us to focus on the problem of complications of classical therapy for psoriasis and the intricacies of prescribing both topical and systemic drugs. Systemic therapy requires the development of algorithms based on objective diagnostic criteria and the results of studies on the effectiveness and safety of modern drugs in pediatric practice.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
Denis V. Zaslavsky
St. Petersburg State Pediatric Medical University
Author for correspondence.
Email: Venereology@gmail.com
ORCID iD: 0000-0001-5936-6232
SPIN-code: 5832-9510
MD, PhD, Dr. Sci. (Med.), Professor, Department of Dermatovenereology
Russian Federation, Saint PetersburgIgor N. Chuprov
St. Petersburg State North-Western Medical University named after I.I. Mechnikov
Email: Igorchuprov@gmail.com
SPIN-code: 2423-6196
MD, PhD, Dr. Sci. (Med.), Professor, Department of the Pathological Anatomy
Russian Federation, Saint PetersburgRuslan A. Nasyrov
St. Petersburg State Pediatric Medical University
Email: rrmd@mail.ru
ORCID iD: 0000-0001-8120-2816
SPIN-code: 5446-0950
MD, PhD, Dr. Sci. (Med.), Professor, Head, Department of Pathological Anatomy with a Course of Forensic Medicine
Russian Federation, Saint PetersburgOlga L. Krasnogorskaya
St. Petersburg State Pediatric Medical University
Email: krasnogorskaya@yandex.ru
SPIN-code: 2460-4480
MD, PhD, Associate Professor, Department of Pathological Anatomy with a Course of Forensic Medicine
Russian Federation, Saint PetersburgElena S. Bolshakova
St. Petersburg State Pediatric Medical University
Email: Bolena2007@rambler.ru
Head, Department of Dermatovenereology
Russian Federation, Saint PetersburgElena S. Manylova
St. Petersburg State Pediatric Medical University
Email: Tulechka78@mail.ru
Dermatovenereologist
Russian Federation, Saint PetersburgOlga K. Mineeva
St. Petersburg State Pediatric Medical University
Email: mine@yandex.ru
Clinical Dermatovenereologist
Russian Federation, Saint PetersburgLyudmila N. Drozdova
St. Petersburg State Pediatric Medical University
Email: Luddrozd@mail.ru
Dermatovenereologist
Russian Federation, Saint PetersburgKsana V. Shternliht
St. Petersburg State Pediatric Medical University
Email: Sara.shtern70@mail.ru
Pediatrician, Head of the Department, Head of the children reception Department
Russian Federation, Saint PetersburgAkmal A. Sidikov
Fergana Medical Institute of Public Health
Email: Medik-85@bk.ru
ORCID iD: 0000-0002-0909-7588
SPIN-code: 3812-8400
MD, PhD, Dr. Sci. (Med.), Professor, Rector
Uzbekistan, FerganaKseniya A. Kovalenko
St. Petersburg State Pediatric Medical University
Email: Zgbv00@mail.ru
SPIN-code: 4466-9583
Student, Department of the Dermatovenereology
Russian Federation, Saint PetersburgAlena P. Brazhnikova
St. Petersburg State Pediatric Medical University
Email: Alenapetrovna919@gmail.com
ORCID iD: 0000-0002-9800-7133
SPIN-code: 1791-0736
Dermatovenereologist, Assistant
Russian Federation, Saint PetersburgDariya V. Kozlova
St. Petersburg State Pediatric Medical University
Email: Dashaucheneya@yandex.ru
ORCID iD: 0000-0002-6942-2880
SPIN-code: 3783-8565
Student, employee, Department of Dermatovenereology
Russian Federation, Saint PetersburgReferences
- Baranov AA, Volodin NN, Samsygina GA, et al. Ratsional’naya farmakoterapiya detskikh zabolevanii. Moscow: Litterra; 2007. 1163 p. (In Russ.)
- Brazhnikova AP, Paneyzkh MB, Gorlanov IA, et al. Sneddon — Wilkinson subcorneal pustulosis or IgA pemphigus? Farmateka. 2021;28(8):156–161. (In Russ.) doi: 10.18565/pharmateca.2021.8.156-161
- Vasiliev AG, ZaslavskyDV, TrashkovAP, et al. Сhanges in the hormonal status of patients with focal psoriasis vulgaris. Vestnik Dermatologii i Venerologii. 2011;5:88–90. (In Russ.)
- Gorbunova VN. Molecular genetics – the way to individual personalized medicine. Pediatrician (St. Petersburg) 2013;4(1):115–121. (In Russ.) doi: 10.17816/PED41115-121
- Zaslavsky DV, Ravodin RA, Tatarskaya OB, et al. Erythroderma: the modern questions of diagnostics and treatment. Pediatician (St. Petersburg). 2014;5(1):97–102 (In Russ.)
- Zaslavskii DV, Kharbediya ShD, Khvedelidze MG, et al. Rezul’taty otsenki patsientami deyatel’nosti meditsinskogo personala. Proceedings of the IX Russian-German Scientific and Practical Conference of the Forum. R. Koch and I.I. Mechnikov “Novye gorizonty: innovatsii i sotrudnichestvo v meditsine i zdravookhranenii”. Kravchenko OV, Khan G, Eds. Novosibirsk: Sibirskii tsenter delovykh tekhnologii; 2010. P. 28–29. (In Russ.)
- Kostinov MP, Bulgakova VA, Abaeva ZR, et al. Immunokorrekciya v pediatrii. Moscow: Medicina dlya vsekh; 2001. 237 p. (In Russ.)
- Ministerstvo zdravookhraneniya Rossiyskoi Federatsii. Klinicheskie rekomendatsii. Psoriaz u detei i vzroslykh. 2020. 66 p. (In Russ.) Available from: https://bazanpa.ru/minzdrav-rossii-klinicheskie-rekomendatsii-ot01012020-h4782548/
- Murashkin NN, Ivanov AM, Zaslavskн DV, Kamilova TA. Studies on effectiveness and safety of system retinoids use in therapy of adolescent acne. Vestnik dermatologii i venerologii. 2010;5:112–116.
- Rodionov AN, Zaslavsky DV, Chuprov IN, et al. Dermatopatologiya vospalitelnykh zabolevaniy kozhy. Тashkent: Baktria Press; 2014. 208 p. (In Russ.)
- Yuryev VK, Zaslavsky DV, Vitenko NV, et al. Some results of the assessment of patients of the quality of medical care. The Scientific Notes of the Pavlov University. 2010;17(2):5–7. (In Russ.)
- Menter A, Cordoro KM, Dawn MR, et al. Joint American Academy of Dermatology – National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis in pediatric patients. J Am Acad Dermatol. 2020:82(1):161–201. doi: 10.1016/j.jaad.2019.08.049
- Andrulonis R, Ferris LK. Treatment of severe psoriasis with ustekinumab during pregnancy. J Drugs Dermatol. 2012;11(10):1240.
- Bachelez H. Pustular psoriasis: the dawn of a new era. Acta Derm Venereol. 2020;100:adv00034. doi: 10.2340/00015555–3388
- Benson JM, Peritt D, Scallon BJ, et al. Discovery and mechanism of ustekinumab: a human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders. MAbs. 2011;3(6):535–545. doi: 10.4161/mabs.3.6.17815
- Buttgereit F, Da Silva JAP, Boers M, et al. Standardised nomenclature for glucocorticoid dosages and glucocorticoid treatment regimens: current questions and tentative answers in rheumatology. Ann Rheum Dis. 2002;61(8):718–722. doi: 10.1136/ard.61.8.718
- Degos R, Civatte J, Arrouy M. Psoriasis et psoriasis pustuleaxatype deerythemeannulaire centrifuge (3 cas). Bull Soc Fr Dermatol Syphiligr. 1966;73(4): 356–358.
- Falto-Aizpurua LA, Martin-Garcia RF, CarrasquilloOY, et al. Biological therapy for pustular psoriasis: a systematic review. Int J Dermatol. 2020;59(3):284–296. doi: 10.1111/ijd.14671
- Fujita H, Terui T, Hayama K, et al. Japanese guidelines for the management and treatment of generalized pustular psoriasis: the new pathogenesis and treatment of GPP. J Dermatol. 2018;45(11):1235–1270. doi: 10.1111/1346–8138.14523
- Goenaga-Vázquez Y, Lauk KC, et al. Therapeutic challenges in managing pediatric psoriasis. Int J Women’s Dermatol. 2020:7(3):314–318. doi: 10.1016/j.ijwd.2020.09.012
- Golubnitschaja O, Costigliola V, Benini A, et al. General Report & Recommendations in Predictive, Preventive and Personalised Medicine 2012: White Paper of the European Association for Predictive, Preventive and Personalised Medicine. EPMA J. 2012;3(1):14. doi: 10.1186/1878-5085-3-14
- Hussain S, Berki DM, Choon SE, et al. IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis. J Allergy Clin Immunol. 2015;135(4):1067–1070. doi: 10.1016/j.jaci.2014.09.043
- Karamfilov T, Wollina U. Juvenile generalized pustular psoriasis. Acta Derm Venereol. 1998;78(3):220. doi: 10.1080/000155598441576
- Kittler NW, Cordoro KM. Pediatric Psoriasis Comorbidities. Skin Therapy Lett. 2020;25(5):1–6.
- Lapiere S. Deux cas de psoriasis recidivants a elements evoluant de faconanoralement: Rapideenquelequesjours. Arch Belg Dermatol Syphiligr. 1959;15(1): 7–12.
- Levin EC, Debbaneh M, Koo J, et al. Biologic therapy in erythrodermic and pustular psoriasis. J Drugs Dermatol. 2014;13(3):342–354.
- Mansouri B, Richards L, Menter A. Treatment of two patients with generalized pustular psoriasis with the interleukin-1 beta inhibitor gevokizumab. Br J Dermatol. 2015;173(1):239–241. doi: 10.1111/bjd.13614
- Mehta AB, Nadkarni NJ, Patil SP, et al. Topical corticosteroids in dermatology. Indian J Dermatol Venereol Leprol. 2016;82(4):371–378. doi: 10.4103/0378-6323.178903
- Michalek IM, Loring B, John SM. A systematic review of worldwide epidemiology of psoriasis. J Eur Acad Dermatol Venereol. 2017;31(3):205–212. doi: 10.1111/jdv.13854
- Milian A, Katchoura V. Psoriasis pustuleux généralisé. Bull Soc Fr Dermatol Syph. 1933;40:851–853. (In French.)
- Navarini AA, Burden AD, Capon F, et al. ERASPEN Network: European consensus statement on phenotypes of pustular psoriasis. J Eur Acad Dermatol Venereol. 2017;31(11):1792–1799. doi: 10.1111/jdv.14386
- Neve S, Kirtschig G. Elastotic striae associated with striae distensae after application of very potent topical corticosteroids. Clin Exp Dermatol. 2006;31(3):461–462. doi: 10.1111/j.1365-2230.2006.02090.x
- Robinson A, Van Voorhees AS, Hsu S, et al. Treatment of pustular psoriasis: from the Medical Board of the National Psoriasis Foundation. J Am Acad Dermatol. 2012;67(2):279–288. doi: 10.1016/j.jaad.2011.01.032
- Sfikakis PP, Iliopoulos A, Elezoglou A, et al. Psoriasis induced by anti-tumor necrosis factor therapy: a paradoxical adverse reaction. Arthritis Rheum. 2005;52(8):2513–2518. doi: 10.1002/art.21233
- Sussman M, Napodano A, Huang S, et al. Pustular Psoriasis and Acute Generalized Exanthematous Pustulosis. Medicina (Kaunas). 2021;57(10):1004. doi: 10.3390/medicina57101004
- Tsuruta D, Ishii N, Hamada T, et al. IgA pemphigus. Clin Dermatol. 2011;29(4):437–442. doi: 10.1016/j.clindermatol.2011.01.014
- Uva L, Miguel D, Pinheiro C, et al. Mechanisms of Action of Topical Corticosteroids in Psoriasis. Int J Endocrinol. 2012;2012:561018.
- Viguier M, Guigue P, Pages C, et al. Successful treatment of generalized pustular psoriasis with the interleukin-1-receptor antagonist Anakinra: lack of correlation with IL1RN mutations. Ann Int Med. 2010;153(1):66–67. doi: 10.7326/0003-4819-153-1-201007060-00030
- Watts PJ, Khachemoune A. Subcorneal pustular dermatosis: a review of 30 years of progress. Am J Clin Dermatol. 2016;17(6):653–671. doi: 10.1007/s40257-016-0202-8
- Von Zumbusch L. Psoriasis and pustuloses exanthema. Arch Dermatol Syphilol. 1910;99:335–346.