The effectiveness of anti-helicobacter therapy in the treatment of chronic gastroduodenal pathology in children with different levels of compliance

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Abstract

At the present time, the therapy of most diseases requires special attention not only from the treating physician, but also from the patient. In turn, in the treatment of children, the monitoring of compliance with the treatment is carried out not by the patient, but by his parents who control the regimen of taking medications. The aim of the study was to determine the efficiency of traditional anti-H. pylori regimen in the treatment of chronic gastroduodenal pathology in children with various level of parental compliance. 80 children of school age suffering from peptic ulcer disease duodenal ulcer associated with H. pylori from families with different levels of parental compliance were examined. The traditional anti-H. pylori therapy scheme containing omeprazole, clarithromycin lasting 14 days was prescribed for all children with chronic gastroduodenal pathology. It is established that strict adherence to the regimen and duration of administration of prescribed drugs allows achieving a high level of eradication of H. pylori even with the use of the traditional anti-Helicobacter pylori. Conducting a “compliance training” before starting therapy is an important factor that increases the level of parental compliance in patients with inflammatory-destructive diseases of the stomach and duodenum. Establishment of interpersonal relationships in the “doctor-patient-parent” system, working with parents, aimed at explaining the essence of the disease, the consequences of the disease, treatment tactics are an important stage in the therapy of a sick child.

About the authors

Andrew V. Nalyotov

Donetsk National Medical University named after M. Gorky

Author for correspondence.
Email: nalyotov-a@mail.ru

MD, PhD, Dr Med Sci, Associate Professor, Department of Pediatrics and Childhood Infections

Ukraine, Donetsk

Sergey V. Nalyotov

Donetsk National Medical University named after M. Gorky

Email: nalyotov-a@mail.ru

MD, PhD, Dr Med Sci, Professor, Head, Department of Pharmacology and Clinical Pharmacology named after prof. I.V. Komissarov

Ukraine, Donetsk

Anna S. Barinova

Donetsk National Medical University named after M. Gorky

Email: nalyotov-a@mail.ru

Assistant Professor, Department of Pharmacology and Clinical Pharmacology named after prof. I.V. Komissarov

Ukraine, Donetsk

Oleg G. Gorshkov

Donetsk National Medical University named after M. Gorky

Email: nalyotov-a@mail.ru

PhD, Associate Professor, Medical Physics, Mathematics and Informatics Department

Ukraine, Donetsk

References

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Supplementary files

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2. Fig. 1. The comparison of effective Helicobacter pylori eradication rates between comparison groups

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Copyright (c) 2018 Nalyotov A.V., Nalyotov S.V., Barinova A.S., Gorshkov O.G.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
 


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