Clinical and laboratory peculiarities of combined clinical course of metabolic and articular syndromes
- 作者: Gorbunova D.1, Morgunova Z.2, Uryasyev O.1
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隶属关系:
- Ryazan State Medical University
- Municipal Clinical Hospital №11
- 期: 卷 26, 编号 2 (2018)
- 页面: 229-237
- 栏目: Original study
- URL: https://journals.rcsi.science/pavlovj/article/view/9095
- DOI: https://doi.org/10.23888/PAVLOVJ2018262229-237
- ID: 9095
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详细
Aim. To identify clinical and laboratory peculiarities of a combined clinical course of metabolic and articular syndromes.
Materials and Methods. In the research 126 individuals participated. They were arranged into 3 groups: the 1st group included 46 patients with comorbid pathology, the 2nd group – 44 patients with metabolic syndrome, and the 3d group – 36 patients with articular syndrome. The following parameters were evaluated: anthropometric data (height, body mass, body mass index, waist circumference), lipid spectrum, glycohemoglobin, nonspecific markers of inflammation, daily profile of arterial pressure.
Results. In the group with comorbid pathology higher average values of body mass were recorded – 115.8 [60;140] kg in comparison with the 2nd and 3d groups – 93.5 [72;130] and 71.5 [58;98] kg, respectively; erythrocyte sedimentation rate – 18.3 [5;34] mm/h was reliably higher than in the 2nd group (11.5 [2;24] mm/h), and median cholesterol (6.18 [5,39;6,85] mmol/L) was higher than in the 3d group (4.82 [3,48;5,61] mmol/L). In the 1st and 2nd groups higher average values of systolic arterial pressure were recorded in comparison with the 3d group – 158,5 [120;190]; 154,6 [115;190] and 126,4 [96;168] mm Hg, respectively.
Conclusions. In patients with combined metabolic and articular syndromes higher values of body mass and systolic arterial pressure were identified. Based on the laboratory findings, parameters of cholesterol and erythrocyte sedimentation rate were higher in patients with comorbid condition than in those with the isolated pathologies.
作者简介
Dar'ja Gorbunova
Ryazan State Medical University
编辑信件的主要联系方式.
Email: darya.solomatina.89@mail.ru
ORCID iD: 0000-0002-8232-2753
SPIN 代码: 8125-8234
PhD Student of the Department of Faculty Therapy with Courses of Endocrinology, Clinical Pharmacology, Occupational Diseases
俄罗斯联邦, 9, Vysokovoltnaja str., Ryazan, 390026Zinaida Morgunova
Municipal Clinical Hospital №11
Email: darya.solomatina.89@mail.ru
ORCID iD: 0000-0002-2159-0287
SPIN 代码: 4126-4049
Еndocrinologist
俄罗斯联邦, RyazanOleg Uryasyev
Ryazan State Medical University
Email: darya.solomatina.89@mail.ru
ORCID iD: 0000-0001-8693-4696
SPIN 代码: 7903-4609
MD, Grand PhD, Professor, Head of the Department of Faculty Therapy with Courses of Endocrinology, Clinical Pharmacology, Occupational Diseases
俄罗斯联邦, 9, Vysokovoltnaja str., Ryazan, 390026参考
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