Email this article MORPHOGENESIS ABDOMINAL AORTIC ANEURYSM
- Issue: Vol 21, No 2 (2013)
- Pages: 7-12
- Section: Articles
- URL: https://journals.rcsi.science/pavlovj/article/view/5275
- DOI: https://doi.org/10.17816/PAVLOVJ201327-12
- ID: 5275
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Abstract
This paper presents data on morphological changes in the wall of abdominal aortic aneurysms in order to study the importance of the inflammatory response in the development of an aneurysm. It is found that chronic inflammation plays a major role in the pathogenesis of abdominal aortic aneurysm formation. In the wall of the aneurysm revealed extensive inflammatory infiltrates of lymphocytes, macrophages, which are the main source of metalloproteinases that cause degeneration of elastin and collagen, which leads to the destruction of the wall structure and dilatation of the aorta.
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- Константинов Б.А. Аневризма аорты с аортальной недостаточностью: патоморфология и хирургическая тактика / Б.А. Константинов, Ю.В. Белов, М.А. Соборов // Кардиология. - 1999. - № 11. - С. 4-8.
- Тихановская Е.О. Современные взгляды на этиологию и патогенез аневризм брюшной аорты / Е. О. Тихановская // Вестн. хирургии им. Грекова. - 2009. -№ 5. - С. 116-119.
- Этиология и патогенез аневризмы брюшной аорты / И.И. Сухарев [и др.] // Клінічна медицина. - 1995. - № 8. - С. 25-28.
- Хем А. Гистология / А. Хем, Д. Кормак. - М.: Мир, 1983. - С. 244.
- Combined effects of HDL cholesterol triglyceride and total cholesterol concentrations on 18- year risk of atherosclerotic disease / C.M. Burchfil [et al.] // Circulation Livingstjne. - 1995. - Vol. 92, № 6. - P. 1430-1436.
- Cystatin C in deficiency in human aterosclerosis and aortic aneurysms / G.P. Shi [et al.] // J. Clin Invest. - 1999. - Vol. 104, № 9. - Р. 191-197.
- Death of smooth muscle celes and expression of mediators of apoptosis by T-lymphocytes in human abdominal aortic aneurysms / T.L. Henderson [et al.] // Circulation. - 1999. - Vol. 99, № 1. - Р. 96-104.
- Hollier L.H. Recommended indications for operative treatment of abdominal aortic aneurysms: report of a subcommittee of the Joint Council of the Society for vascular surgery and the north American Chapter of the international Society for cardio vascular surgery / L.H. Hollier, L.M. Taylor, I. Ochsner // J. Vasc. Surg. - 1992. - Vol. 15, № 6. - P. 1046-1056.
- Human abdominal aortic aneurysms, immunophenotypic analysis suggesting an immunemediated risponse / J.A. Radosevich [et al.] // Am J. Pathol. - 1990. - Vol. 137, № 5. - P. 1199-1213.
- Li P.F. Reactive oxygen species induce apoptosis of vascular smooth muscle cell / P.F. Li, R. Dietz, F.R. von Harsdor // FEBS Lett. - 1997. - Vol. 404. - Р. 249-252.
- Pasquintlli G. An immunol study of inflammatory abdominal aortic aneurysms / G. Pasquintlli, P. Preda, M. Gargiulo // J. Submicrosc Cytol Pfthol. - 1993. - Vol. 25, № 1. - P. 103-112.
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