Email this article L-NORVALIN AND ISCHEMICAL PRECONDITIONING ACTION MECHANISMS ANALYSIS AT LIVER ISCHEMIA/REPERFUSION
- Issue: Vol 21, No 1 (2013)
- Pages: 56-59
- Section: Articles
- URL: https://journals.rcsi.science/pavlovj/article/view/5128
- DOI: https://doi.org/10.17816/PAVLOVJ2013156-59
- ID: 5128
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Abstract
In this article ischemical preconditioning and L-norvalin efficacy and mechanisms of action pharmacological analysis at liver experimental ischemia/reperfusion were made. During investigation ischemical preconditioning high effectiveness totally wasn’t blocked by glibenclamide showed. L-norvaline also showed marked hepatoprotective effect abolished by glibenclamide just partly.
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- Bolli R. Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research / R. Bolli // J. Mol. Cell. Cardiol. - 2001. - Vol. 33. -Р. 1897-1918.
- Cohen, M.V. Adenosine: trigger and mediator of cardioprotection / M.V. Cohen, J.M. Downey // Basic. Res. Cardiol. -2008. - Vol. 103, № 3. - P. 203-215.
- Downey J.M. Signaling pathways in ischemic preconditioning / J.M. Downey, A.M. Davis, M.V. Cohen // Heart. Fail. Rev. - 2007. - Vol. 12. - P. 181-188.
- Kirino T. Ischemic tolerance / T. Kirino // J. Cerebr. Blood. Flow. Metabol. - 2002. - Vol. 22. - P. 1283-1296.
- Murry C.E. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium / С.Е. Murry, R.B. Jennings, К.А. Reimer // Circulation. -1986. - Vol. 14. - Р. 1124-1136.
- Rezkalla S.H. Preconditioning in humans / S.H. Rezkalla, R.A. Kloner // Heart. Fail. Rev. - 2007. - Vol. 12. - P. 201-206.
- Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis / Ran Meng [et al.] // Neurology. -2012. - Vol. 79. - P. 1853-1861.
