INTERFERON GAMMA-CYTOKINE WITH ANTIVIRAL, IMMUNOMODULATORY AND ANTITUMOR ACTION

Abstract

Interferon gamma is a unique drug with anti-virus, anti-tumor and immunomodulatory activity. Thanks to the latter its quality interferon gamma was added to cytokines - regulators of immune responses. The study of this interesting cytokine can open up broad prospects for the treatment of patients not only with lymphoproliferative diseases, but patients with cancer and infectious diseases.

References

  1. Возможности использования интерферона -гамма в комплексной терапии больных хроническим гепатитом С / Т.В. Сологуб [и др.] // Инфекционные болезни. - 2013. - Т. 11, № 2. - С. 74-80.
  2. Иола А.И. Сравнительная клинико-лабораторная и эпидемиологическая характеристика ВИЧ/СПИД инфекции, ассоциированной с туберкулезом в Нигерии и России: автореф. дис. д-ра мед. наук / А.И. Иола. - М., 2006. - 30 с.
  3. Bach E.A. The IFN gamma receptor: a paradigm for cytokine receptor signaling / E.A. Bach, M. Aguet, R.D. Schreiber // Annu. Rev. Immunol. - 1997. - № 15. -Р. 563-591.
  4. Cellular responses to interferon-gamma / U. Boehm [et al.] // Annu. Rev. Immunol. - 1997. - № 15. - Р. 749-795.
  5. IFN-gamma production by antigen-presenting cells: mechanisms emerge / D.M. Frucht [et al.] // Trends Immunol. -2001. - № 22. - Р. 556-560. Isaacs A. Virus interference. I. The interferon / A. Isaacs, J. Lindermann // Proc. R. Soc. Lond. B Biol. Sci. - 1957. - № 147. - Р. 258-267.
  6. Subramaniam P.S. So many ligands, so few transcription factors: a new paradigm for signaling through the STAT transcription factors / P.S. Subramaniam, B.A. Torres, H.M. Johnson // Cytokine. -2001. - № 15. - Р. 175-187.

Copyright (c) 2014 Sologub T.V., Tsvetkov V.V., Deeva E.G.

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