Email this article Morphological changes of the liver parenchyma after embolization of the right branch of the portal vein
- Issue: Vol 23, No 1 (2015)
- Pages: 32-40
- Section: Articles
- URL: https://journals.rcsi.science/pavlovj/article/view/4601
- DOI: https://doi.org/10.17816/PAVLOVJ2015132-40
- ID: 4601
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Abstract
To determine the morphological changes of the parenchyma of the right and the left lobe of the liver after embolization of the right branch of the portal vein. Material and Methods: Embolization of the right branch of the portal vein was performed in 15 patients. All patients by CT of the abdomen future liver remnant (FLR) sizes were less than 30% (from 17 to 27%) in average - 19,78%. Before and after the procedure was performed a biopsy of the right and the left lobe of the liver, followed by assessment of morphological changes of the parenchyma. Results: The volume of the liver after portoembolizatsii on average increased by 12,5%, the volume of the left lobe of the liver increased by an average of 41,7%. Expected hypertrophy of the left lobe of the liver is not obtained in one patient (6,66%). In the remaining 14 patients (93,3%) the size of the left lobe of the liver, and increased by more than 30%. Radical surgical treatment performed 9 (60%) patients. Study of histological changes after hepatic parenchyma portoembolization showed that hypertrophy of the contralateral lobe of the liver, occurs due to hypertrophy of the existing and the emergence of new, functionally active hepatocytes. The use of embolization of the right branch of the portal vein in most cases allows for vicarious hypertrophy of the left lobe of the liver due to hypertrophy of the existing and the emergence of new, functionally active hepatocytes.
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