A complex case of diagnosis of Conn’s syndrome

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Abstract

The primary hyperaldosteronism also known as Conn’s syndrome, is a rarely diagnosed disease that commonly runs under a ‘mask’ of ischemic heart disease and the primary arteria hypertension (AH). Nevertheless, the incidence of the given pathology among all patients with AH makes almost 17%. On the other hand, the absence of specific clinical manifestations of the disease makes its timely and correct diagnosis difficult which is fraught with serious complications. In the article a clinical case of Conn’s syndrome and peculiarities of its diagnosis are described.

About the authors

Grigory A. Ignatenko

M. Gorky Donetsk National Medical University

Email: gai-1959@mail.ru
ORCID iD: 0000-0002-1155-563X

MD, PhD, Professor, Сorrespondent Member of National Academy of Medical Sciences of Ukraine, Honored Scientist and Technician of Ukraine, Rector, Head of the Department of Propaedeutic and Internal Medicine

Ukraine, 83003, Donetsk, Ilyicha Ave., 16

Ilya S. Grekov

M. Gorky Donetsk National Medical University

Author for correspondence.
Email: ilya.grekov.1998@gmail.com
ORCID iD: 0000-0002-6140-5760

Student

Ukraine, 83003, Donetsk, Ilyicha Ave., 16

Marina V. Grushina

M. Gorky Donetsk National Medical University

Email: grushinamarina@inbox.ru
ORCID iD: 0000-0003-3670-3376

MD, PhD, Associate Professor of the Department of Propaedeutic and Internal Medicine

Ukraine, 83003, Donetsk, Ilyicha Ave., 16

Anna V. Dubovyk

M. Gorky Donetsk National Medical University

Email: dubovyk-anna@mail.ru
ORCID iD: 0000-0002-8753-3824

PhD, Associate Professor of the Department of Propaedeutic and Internal Medicine

Ukraine, 83003, Donetsk, Ilyicha Ave., 16

References

  1. Svishchenko EP, Kovalenko VN. Gipertonicheskaya bolezn’. Vtorichnyye gipertenzii. Kiyev: Lybid’; 2002. P. 178-93.
  2. Kalyagin AN, Beloborodov VA, Maksikova TM. Symptomatic arterial hypertension associated with primary hyper-aldosteronism. Arterial Hypertension. 2017;23(3):224-30. doi: 10.18705/1607-419x-2017-23-3-224-230
  3. Kettyle WM, Arky RA. Endocrine pathophysiology. Philadelphia; 1998. P. 275-94.
  4. Galati SJ, Cheesman KC, Springer-Miller R, et al. Prevelence of primary aldosteronism in an urban hypertensive pop-ulation. Endocrine Practice. 2016; 22(11):1296-302. doi: 10.4158/E161332.OR
  5. Korotin AS, Posnenkova OM, Kiselev AR, et al. Pervichnyy giperal’dosteronizm pod maskoy essen-tsial’noy arteri-al’noy gipertenzii: redkoye zabole-vaniye ili redkiy diagnoz? Russkiy Meditsinskiy Zhurnal. Kardiologiya. 2015;(15): 908-12.

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2. Fig. 1. V1-V6 leads of ECG of female patient S. with evident hypokalemia

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Copyright (c) 2020 Ignatenko G.A., Grekov I.S., Grushina M.V., Dubovyk A.V.

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