Effectiveness of mediastinal lymphadenectomy in surgical treatment of generalized destructive pulmonary tuberculosis
- 作者: Papkov A.V.1, Giller D.B.2, Dobin V.L.1
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隶属关系:
- Ryazan State Medical University
- The State Education Institution of Higher Professional Training The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation
- 期: 卷 26, 编号 4 (2018)
- 页面: 511-518
- 栏目: Original study
- URL: https://journals.rcsi.science/pavlovj/article/view/10845
- DOI: https://doi.org/10.23888/PAVLOVJ2018264511-518
- ID: 10845
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详细
Bronchopleural complications after pneumonectomy in generalized destructive tuberculosis are associated with the presence of intrathoracic lymph nodes (ITLN) with caseous alterations.
Aim. To improve the effectiveness of surgical treatment of patients with generalized destructive pulmonary tuberculosis by development and introduction of the method of mediastinal lymphadenectomy in tuberculous lesion of mediastinal lymph nodes.
Materials and Methods. Results of surgical treatment of 515 patients with generalized destructive pulmonary tuberculosis were analyzed. In 274 of them the surgical treatment was supplemented with mediastinal lymphadenectomy (the main group). In the control group (241 patients) only resection was performed without removing lymph nodes.
Results. Analysis of the postoperative course of the disease in both groups of patients (with mediastinal lymphadenectomy and without it) showed that bronchopleural complications occurred in 7 (2.6%) cases in the main group and in 30 (12.4%, p<0.05) cases in the control group. In the main group exacerbation of the specific process was noted in 1 patient (0.4%), and in comparison group in 9 patients (3.7%, p<0.05). Elimination of macroscopically altered ITLN in widespread destructive tuberculosis permitted to reduce the complications rate in the postoperative period by 64.8% (p<0.05). Indications to removal of IHLN included: a) enlargement of ITLN (>2 sm) and in duration; b) fusion with the surrounding tissues, softening of the node tissue in its caseous melting, c) existence of yellowish or whiter in comparison with the surrounding tissue inclusions in the node being manifestations of tuberculous granuloma. In histological, cytological and bacteriological examination, these macroscopic signs in 97% of cases indicated active tuberculosis of mediastinal lymph nodes.
Conclusions. In 97% of cases, widespread destructive secondary pulmonary tuberculosis runs with an active specific process in mediastinal lymph nodes which makes it reasonable to perform a selective lymphadenectomy in such group of patients. Secondary damage of different groups of intrathoracic lymph nodes by the active process depended on localization of lung destructions and occurred along the routes of lymph drainage from them. Reliable signs of active tuberculous of ITLN include: more than 2.0 cm lymph node enlargement, in duration, periadenitis, fluctuation and in homogeneity. Removal of macroscopically altered intra-thoracic lymph nodes in widespread destructive pulmonary tuberculosis permits to reduce the rate of complications in the postoperative period by 64.8%.
作者简介
Aleksandr Papkov
Ryazan State Medical University
编辑信件的主要联系方式.
Email: avpapkov@mail.ru
ORCID iD: 0000-0003-2988-990X
SPIN 代码: 4902-5864
Researcher ID: L-4679-2018
MD, PhD, Professor of the Department of Phthisiology with a Course of Radiation Diagnosis
俄罗斯联邦, 9,Vysokovoltnaja,Ryazan,390026Dmitriy Giller
The State Education Institution of Higher Professional Training The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation
Email: vestnik@rzgmu.ru
ORCID iD: 0000-0003-1946-5193
SPIN 代码: 2955-6303
Researcher ID: L-5841-2018
MD, PhD, Professor, Head of the Department of Phthisiology with a Course of Thoracic Surgery
俄罗斯联邦, 8-2, Trubetskaya street, Moscow, 119992Vitaliy Dobin
Ryazan State Medical University
Email: vestnik@rzgmu.ru
ORCID iD: 0000-0002-6512-558X
SPIN 代码: 7454-9457
Researcher ID: S-8143-2016
MD, PhD, Professor, Head of the Department of Phthisiology with a Course of Radiation Diagnosis
俄罗斯联邦, 9,Vysokovoltnaja,Ryazan,390026参考
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