Clinical-social and psychological-pedagogical approaches in the prevention and treatment of obesity and metabolic syndrome in children

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

Childhood obesity is an acute problem in the European Region, including countries participating in the World Health Organization's European Childhood Obesity Surveillance Initiative. According to their data, the proportion of overweight children reaches 43%. Overweight and obesity, as well as related diseases, are largely preventable. For this reason, the prevention of childhood obesity should be given top priority. Adolescence obesity has reached epidemic proportions worldwide, with the prevalence of complicated obesity increasing at least fourfold over the past 35 years. Most obese adolescents also have excess body fat mass in adulthood, which increases the risk of obesity-related complications, such as type 2 diabetes and cardiovascular disease, and negatively affects social and psychological health. In modern conditions the prevention of the overweight and obesity formation among schoolchildren is not systemic: no attention is paid to the identification of possible risk factors, no unified approaches exist among specialists of various levels to the methodology for preventing the overweight and obesity formation, rational hygienic measures for preventing obesity are not always implemented, the causes of late diagnostics of overweight and obesity among schoolchildren by pediatricians are not fully analyzed, the motivation of children and parents to change their lifestyle in order to fight overweight are not sufficiently studied. The systemic implementation of such preventive measures could help to reduce the number of overweight schoolchildren and improve the health of the child population.

About the authors

Victoria A. Dudareva

Rostov State Medical University

Email: zozh@rostgmu.ru
ORCID iD: 0000-0002-5132-924X

Assistant, Depart. of Healthy Lifestyle and Dietetics

Russian Federation, Rostov-on-Don, Russia

Anastasiya A. Shikaleva

Kazan State Medical University

Author for correspondence.
Email: shikaleva@gmail.com
ORCID iD: 0000-0003-1798-0490

Postgrad. Student, Depart. of general hygiene

Russian Federation, Kazan, Russia

Maksim L. Maksimov

Kazan State Medical Academy, a branch of the Russian Medical Academy of Postgraduate Education; Russian National Research Medical University named after N.I. Pirogov; Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University

Email: maksim_maksimov@mail.ru
ORCID iD: 0000-0002-8979-8084

M.D., D. Sci. (Med.), Prof., Head of Depart., Depart. of Clinical Pharmacology and Pharmacotherapy

Russian Federation, Kazan, Russia; Moscow, Russia; Kazan, Russia

Irina G. Dyadikova

Rostov State Medical University

Email: zozh@rostgmu.ru
ORCID iD: 0000-0003-0327-8350

M.D., Cand. Sci. (Med.), Assoc. Prof., Head of Depart., Depart. of Healthy Lifestyle and Dietetics Department

Russian Federation, Rostov-on-Don, Russia

Aleksey V. Shulaev

Kazan State Medical University

Email: shulaev8@gmail.com
ORCID iD: 0000-0002-2073-2538
SPIN-code: 3229-1913

M.D., D. Sci. (Med.), Prof., Head of Depart., Depart. of general hygiene, prorector

Russian Federation, Kazan, Russia

References

  1. Materialy s sayta Evropeyskogo regional'nogo byuro VOZ. (Materials from the website of the WHO Regional Office for Europe.) https://www.euro.who.int/__data/assets/pdf_file/0017/215432/Health2020-Long-Rus.pdf (access date: 01.07.2021). (In Russ.)
  2. Vsemirnaya organizatsiya zdravookhraneniya. Ozhirenie i izbytochnyy ves. Informatsionnyy byu­lleten'. (World Health Organization. Obesity and overweight. News bulletin.) https://gateway.euro.who.int/ru/themes/obesity-physical-activity-and-nutrition/infographics/ (access date: 01.07.2021). (In Russ.)
  3. Tutelyan VA, Baturin AK, Kon IYa, Martinchik AN, Uglitskih AK, Korosteleva MM, Toboleva MA, Aleshina IV. Prevalence of overweight and obesity in child population of Russia: multicenter study. Pediatriya. Zhurnal imeni G.N. Spe­ranskogo. 2014;93(5):28–31. (In Russ.)
  4. Kumar S, Kelly AS. Review of childhood obesity: From epidemiology, etiology, and comorbidities to clinical assessment and treatment. Mayo Clin Proc. 2017;92(2):251–265. doi: 10.1016/j.mayocp.2016.09.017.
  5. Mameli C, Mazzantini S, Zuccotti GV. Nutrition in the first 1000 days: The origin of childhood obesity. Int J Environ Res Public Health. 2016;13(9):838. doi: 10.3390/ijerph13090838.
  6. Dutton H, Borengasser SJ, Gaudet LM, Barbour LA, Keely EJ. Obesity in pregnancy: Optimizing outcomes for mom and baby. Med Clin North Am. 2018;102(1):87–106. doi: 10.1016/j.mcna.2017.08.008.
  7. Hill B, Skouteris H, Boyle JA, Bailey C, Walker R, Thangaratinam S, Sundseth H, Stephenson J, Steegers E, Redman LM, Montanaro C, Lim S, Jorgensen L, Jack B, Borges ALV, Bergmeier HJ, Baxter JB, Harrison CL, Teede HJ. Health in preconception, pregnancy and postpartum Global Alliance: International Network Pregnancy ­Priorities for the Prevention of Maternal Obesity and Rela­ted Pregnancy and Long-Term Complications. J Clin Med. 2020;9(3):822. doi: 10.3390/jcm9030822.
  8. Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Morin AM, Yap F, Tan H, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group. Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome. BMC Med. 2017;15(1):50. doi: 10.1186/s12916-017-0800-1.
  9. Vsemirnaya organizatsiya zdravookhraneniya. Ozhirenie i izbytochnyy ves. Informatsionnyy byulleten'. (World Health Organization. Obesity and overweight. News bulletin.) https://www.who.int/ru/news-room/fact-sheets/detail/obesity-and-overweight (access date: 01.07.2021). (In Russ.)
  10. Klini­cheskie rekomendatsii “Ozhirenie u detey”. (Clinical guidelines “Obesity in children”.) Moskva; 2021. https://www.endocrincentr.ru/sites/default/files/specialists/science/clinic-recomendations/kr_ozhirenie_deti.pdf (access date: 01.07.2021). (In Russ.)
  11. Ling C, Rönn T. Epigenetics in human obesity and type 2 diabetes. Cell Metab. 2019;29(5):1028–1044. doi: 10.1016/j.cmet.2019.03.009.
  12. Argueta DA, DiPatrizio NV. Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity. Physiol Behav. 2017;171:32–39. doi: 10.1016/j.physbeh.2016.12.044.
  13. Burns-Whitmore B, Froyen E, Heskey C, Par­ker T, San Pablo G. Alpha-linolenic and linoleic fatty ­acids in the vegan diet: Do they require dietary reference intake/adequate intake special consideration? Nutrients. 2019;11(10):2365. doi: 10.3390/nu11102365.
  14. Shikh EV, Makhova AA. Long-chain ω-3 polyunsaturated fatty acids in the prevention of disea­ses in adults and children: a view of the clinical pharmaco­logist. Voprosy pitaniya. 2019;88(2):91–100. (In Russ.) doi: 10.24411/0042-8833-2019-10022.
  15. Van der Wurff ISM, Meyer BJ, de Groot RHM. Effect of Omega-3 Long Chain Polyunsaturated Fatty Acids (n-3 LCPUFA) supplementation on cognition in children and adolescents: A systematic literature review with a focus on n-3 LCPUFA blood values and dose of DHA and EPA nutrients. Nutrients. 2020;12(10):3115. doi: 10.3390/nu12103115.
  16. Singh JE. Dietary sources of omega-3 fatty acids versus omega-3 fatty acid supplementation effects on cognition and inflammation. Curr Nutr Rep. 2020;9(3):264–277. doi: 10.1007/s13668-020-00329-x.
  17. Skvortsova VA, Borovik TE, Semenova NN, Bushueva TV, Roslavtseva EA, Stepanova TN, Guseva IM, Khodzhieva MV. Sugar and salt in a young child's diet: effect on health. Current pediatrics. 2016;15(6):596–603. (In Russ.) doi: 10.15690/vsp.v15i6.1657.
  18. Guideline: Sugars intake for adults and children. Geneva: World Health Organization; 2015. https://www.ncbi.nlm.nih.gov/books/NBK132015/ (access date: 01.07.2021).
  19. Korovina NA, Zakharova NI, Zaplatnikov AL, Obynochnaya EG. Correction of vitamin and mineral deficiency in children. Meditsinskiy sovet. 2013;(6):94–98. (In Russ.)
  20. Kodentsova VM, Vrzhesinskaya OA, Risnik DV, Nikityuk DB, Tutel'yan VA. Micronutrient status of population of the Russian Federation and possibility of its correction. State of the problem. Voprosy pitaniya. 2017;86(4):113–124. (In Russ.) doi: 10.24411/0042-8833-2017-00067.
  21. Dudareva VA, Shikaleva AA, Maximov ML, Dyadikova IG, Vovk VO, Filimonova IM. The role of the endocannabinoid system in obesity pathogenesis. RMZh. 2020;(1):23–28. (In Russ.)
  22. Martinchik AN, Baturin AK, Keshabyants EE, Fatyanova LN, Semenova YaA, Bazarova LB, Ustinova YuV. Dietary intake analysis of russian children 3–19 years old. Voprosy pitaniya. 2017;86(4):50–60. (In Russ.)
  23. Lir DN, Novoselov VG, Mishukova TA. Nutrition of pre-school children with obesity: a retrospective cross-sectional study. Voprosy sovremennoy pediatrii. 2018;17(3):221–227. (In Russ.) doi: 10.15690/vsp.v17i3.1892.
  24. Chyornaya MG, Kushnareva OE, Fyodorova KYu, Dudareva VA, Dyadikova IG. The main characteristics of the mo­dern diet of children of primary school age. V sb.: Sbornik materialov regional'noy nauchno-prakticheskoy konferentsii studentov i molodykh uchyonykh “Aspekty zdorovogo obraza zhizni lits molodogo vozrasta”. (Collection of materials of the regional scientific-practical conference of students and young scientists “Aspects of a healthy lifestyle of young people”.) Rostov-na-Donu: Rostovskij gosudarstvennyj medicinskij universitet; 2018. р. 36–41. (In Russ.)
  25. Dyadikova IG, Dudareva VA, Ryabkina EA, Bychkov IN, Korotkova TV. Nutrition of children of primary school age at home as a risk factor for the development of alimentary-dependent diseases. Voprosy pitaniya. 2014;83(S3):72. (In Russ.)
  26. Vsemirnaya organizatsiya zdravookhraneniya. Ozhirenie i izbytochnyy ves. (World Health Organization. Obesity and overweight.) https://www.who.int/ru/news-room/fact-sheets/detail/obesity-and-overweight (access date: 01.07.2021). (In Russ.)
  27. Analiz sostoyaniya pitaniya cheloveka (versiya 1.2; GU NII pitaniya RAMN; 2003–2006). Komp’yuternaya test-programma (CD-ROM). (Analysis of the state of human nutrition (version 1.2; State Research Institute of Nutrition of the Russian Academy of Medical Sciences; 2003–2006). Computer test program (CD-ROM). Moscow: NII Pitaniya; 2006. (In Russ.)
  28. Novoderzhkina YuG, Druzhinina VP, Dyadikova IG, Bychkov IN, Ryabkina EA, Dudareva VA. Osnovy dietologii. (Fundamentals of dietetics.) M.: EKSMO; 2011. 416 p. (In Russ.)
  29. Bala­bolkin MI, editor. Endokrinologiya. (Endocrinology.) M.: Universum pablishing; 1998. р. 367–470. (In Russ.)
  30. Ginzburg MM, Kryukov NN. Ozhirenie. (Obesity.) M.: Medpraktika; 2002. р. 19–77. (In Russ.)
  31. Mel'nichenko GA. Obesity in the practice of an endocrinologist. RMZh. 2001;(2):82. (In Russ.)
  32. Pogontseva DV. The idea of the standards of beauty in modern girls. Nauchno-metodicheskiy elektronnyy zhurnal “Kontsept”. 2014;(20):2496–2500. (In Russ.)
  33. Smirnov VV, Leonov GE. Epigenetics: theoretical aspects and practical significance. Lechashchiy vrach. 2016;(12):26–30. (In Russ.)
  34. Waddington CH. The epigenotype. 1942. Int J Epidemiol. 2012;41(1):10–13. doi: 10.1093/ije/dyr184.
  35. Tikhodeyev ON. Epigenetic and eugenetic processes. Uspekhi sovremennoy biologii. 2015;135(6):542–553. (In Russ.)
  36. Mastroeni D, Grover A, Delvaux E, Whiteside C, Coleman PD, Rogers J. Epigenetics mechanisms in Alzheimer’s disease. Neurobiol Aging. 2011;32(7):1161–1180. doi: 10.1016/j.neurobiolaging.2010.08.017.
  37. Belmer SV. The concept of food programming: general provisions and particular examples. Lechashchiy vrach. 2015;(2):78–82. (In Russ.)
  38. Goryacheva OA. Features of nutrition of pregnant and lactating women. RMZh. 2010;(6):386–388. (In Russ.)
  39. Zakharova IN, Lykina YeV. Consequences of improper infant feeding. Voprosy sovremennoy pediatrii. 2007;6(1):40–46. (In Russ.)
  40. Dzgoeva FKh. Intrauterine nutrition: fetal programming of metabolic syndrome. Obesity and metabolism. 2015;12(3):10–17. (In Russ.) doi: 10.14341/omet2015310-17.
  41. Maksimov ML, Dudareva VA, Dyadikova IG, Filimonova IM, Shikaleva AA. Lechenie ozhireniya i metabolicheskogo sindroma: dietoterapiya i farmakoterapiya. (Treatment of obesity and metabolic syndrome: diet therapy and pharmacotherapy.) Kazan': ID MeDDoK; 2020. 56 p. (In Russ.)
  42. Maldonado-Ruiz R, Montalvo-Martínez L, Fuen­tes-Mera L, Camacho A. Microglia activation due to obesity programs metabolic failure leading to type two diabetes. Nutr Diabetes. 2017;7(3):e254. doi: 10.1038/nutd.2017.10.
  43. Berezina MV, Mihaleva OG, Bardymova TP. The obesity: mechanisms of development. Sibirskiy meditsinskiy zhunal (Irkutsk). 2012;(7):15–18. (In Russ.)
  44. Garanina EYu, Gartsman TYu. Influence of complex the­rapy on indicators of anxiety in case of weight loss. Voprosy pitaniya. 2016;85(S2):45–46. (In Russ.)
  45. Randa EN. Panic attacks. Mezhdunarodnyy studencheskiy nauchnyy vestnik. 2016;(4):82–83. (In Russ.)
  46. Romantsova TI. The obesity epide­mic: obvious and probable causes. Obesity and metabolism. 2011;(1):5–19. (In Russ.)
  47. Kornienko EA. Current conception of the link of obesity and intestinal microbiota. Pediatr. 2013;4(3):3–14. (In Russ.) doi: 10.24412/FhG3c-zTKP8.
  48. Ley RE, Bäckhed F, Turnbaugh P, Lozupone CA, Knight RD, Gordon JI. Obesity alters gut microbial eco­logy. Proc Natl Acad Sci USA. 2005;102(31):11070–11075. doi: 10.1073/pnas.0504978102.
  49. Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature. 2006;444(7122):1022–1023. doi: 10.1038/4441022a.
  50. Schwiertz A, Taras D, Schäfer K, Beijer S, Bos NA, Donus C, Hardt PD. Microbiota and SCFA in lean and overweight healthy subjects. Obesity (Silver Spring). 2010;18(1):190–195. doi: 10.1038/oby.2009.167.
  51. Collado MC, Isolauri E, Laitinen K, Salminen S. Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women. Am J Clin Nutr. 2008;88(4):894–899. doi: 10.1093/ajcn/88.4.894.
  52. De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S, Collini S, Pieraccini G, Lionetti P. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci USA. 2010;107(33):14691–14696. doi: 10.1073/pnas.1005963107.
  53. Materialy s sayta FDA. (Materials from the FDA website.) https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-weight-management-drug-patients-aged-12-and-older (access date: 01.07.2021). (In Russ.)
  54. Starostina EG, Karpov YuA. Liraglutide: a new step towards cardiovascular safety and effectiveness of hypoglycemic therapy. Atmosfera. Novosti kardiologii. 2017;(3):23–31 (In Russ.)
  55. Ostroukhova EN, Khmelnitskii OK, Krasilnikova EI, Davidenko KS. The experience with the clinical application of liralgutide (victosa), the first analog of human glucagon-like peptide-1 in the patients with type 2 diabetes mellitus — expanding the range of possibilities. Problems of endocrinology. 2012;58(3):51–55. (In Russ.)
  56. Osmanov IM, Borzakova SN, Vinokurov AV. Obesity in adolescents: possibilities of therapy. Praktika pediatra. 2021;(3):58–64. (In Russ.)
  57. Buchwald H, Oien DM. Metabolic/bariatric surgery worldwide 2011. Obes Surg. 2013;23(4):427–436. doi: 10.1007/s11695-012-0864-0.
  58. Cazzo E, Gestic MA, Utrini MP, Chaim FD, Callejas-Neto F, Pareja JC, Chaim EA. Bariatric surgery in individuals with liver cirrhosis: A narrative review. Rev Assoc Med Bras (1992). 2017;63(2):190–194. doi: 10.1590/1806-9282.63.02.190.
  59. Pratt JSA, Browne A, Browne NT, Bruzoni M, Cohen M, Desai A, Inge T, Linden BC, Mattar SG, Michalsky M, Podkameni D, Reichard KW, Stanford FC, Zeller MH, Zitsman J. ASMBS pediatric metabo­lic and bariatric surgery guidelines. Surg Obes Relat Dis. 2018;14(7):882–901. doi: 10.1016/j.soard.2018.03.019.
  60. Thenappan A, Nadler E. Bariatric surgery in children: Indications, types, and outcomes. Curr Gastroenterol Rep. 2019;21(6):24. doi: 10.1007/s11894-019-0691-8.
  61. Weihrauch-Blüher S, Wiegand S. Risk factors and implications of childhood obesity. Curr Obes Rep. 2018;7(4):254–259. doi: 10.1007/s13679-018-0320-0.
  62. Martin A, Booth JN, Laird Y, Sproule J, Reilly JJ, Saunders DH. Physical activity, diet and other behavioural interventions for improving cognition and school achievement in children and adolescents with obesity or overweight. Cochrane Database Syst Rev. 2018;1(1):CD009728. doi: 10.1002/14651858.CD009728.pub3.
  63. Metodi­cheskie ukazaniya “Ratsional'noe pitanie. Normy fiziolo­gicheskih potrebnostey v energii i pishhevykh veshhestvakh dlya razlichnykh grupp naseleniya Rossiyskoy Federatsii”. (Guidelines “Rational nutrition. Norms of physiological needs for energy and nutrients for various groups of the po­pulation of the Russian Federation”.) MU 2.3.1-0253 — 21. Moskva; 2021. http://www.consultant.ru/document/cons_doc_LAW_395381/ (access date 14.07.2021). (In Russ.)
  64. Katsagoni CN, Papachristou E, Sidossis A, Sidos­sis L. Effects of dietary and lifestyle interventions on ­liver, clinical and metabolic parameters in children and adolescents with non-alcoholic fatty liver disease. Nutrients. 2020;12(9):2864. doi: 10.3390/nu12092864.
  65. Andrews P, Johnson RJ. Evolutionary basis for the human diet: consequences for human health. J Intern Med. 2020;287(3):226–237. doi: 10.1111/joim.13011.
  66. Kiseleva EV, Latyshev OYu, Okminyan GF, Samso­nova LN. Rational nutrition in type 1 diabetes mellitus in children and adolescents. Pediatriya. Prilozhenie k zhurnalu Consilium Medicum. 2018;(2):74–77. (In Russ.) doi: 10.26442/2413-8460_2018.2.74-77.
  67. Maksimov ML, Dudareva VA, Dyadikova IG, Filimonova IM, Shikaleva AA. Lechenie sakharnogo diabeta: dietoterapiya i farmakoterapiya. (Treatment of diabetes mellitus: diet therapy and pharmacotherapy.) Kazan': ID MeDDoK; 2020. 68 p. (In Russ.)
  68. Klinicheskaya farmakologiya i ratsional'naya farmakoterapiya dlya praktikuyushchikh vrachey. (Clinical pharmacology and rational pharmacotherapy for practicing physicians.) Maksimov ML, editor. Kazan': ID MeDDoK; 2021. 948 p. (In Russ.)

Supplementary files

Supplementary Files
Action
1. JATS XML

© 2022 Eco-Vector





This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies