Endotoxinemia and Intensity of Humoral Immunity in Surgical Treatment of Acute Diseases of Extrahepatic Biliferous Tracts
- Authors: Volkov D.E.1,2, Safina N.A.1,3, Tereshchenko V.Y.1, Zinkevich O.D.3,1
-
Affiliations:
- Kazan State Medical University
- , Kazan Research Institute of Epidemiology and Microbiology
- Kazan NIIEM
- Issue: Vol 82, No 3 (2001)
- Pages: 180-183
- Section: Articles
- URL: https://journals.rcsi.science/kazanmedj/article/view/71662
- DOI: https://doi.org/10.17816/kazmj71662
- ID: 71662
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Abstract
The level of systemic endotoxinemia and intensity of antiendotoxine humoral immunity in surgical treatment of acute diseases of extrahepatic biliary tracts are studied. Two groups of patients were examined. The patients with acute cholecystitis complicated by mechanical jaundice were in the first group, the patients with various forms of acute cholecystitis without disorders of bile outflow were in the second group. It is established that the high level of systemic endotoxinemia is found in patients with signs of mechanical jaundice in preoperative period, in this case the level of general blood bilirubine is directly correlated with the level of systemic endotoxinemia in both groups of patients. The decrease of humoral antiendotoxine immunity in preoperative period and its recovery in postoperative period are noted in patients with mechanical jaudice phenomena as the level of systemic endotoxinemia decreases and bile passage into intestine is recovered.
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##article.viewOnOriginalSite##About the authors
D. E. Volkov
Kazan State Medical University;, Kazan Research Institute of Epidemiology and Microbiology
Author for correspondence.
Email: info@eco-vector.com
Department of General Surgery
Russian Federation, Kazan; KazanN. A. Safina
Kazan State Medical University; Kazan NIIEM
Email: info@eco-vector.com
Department of Infectious Diseases, Laboratory of Immunochemistry
Russian Federation, Kazan; KazanV. Y. Tereshchenko
Kazan State Medical University
Email: info@eco-vector.com
Associate Professor, Head of the Department of General Surgery, Department of Biology and Medical Genetics
Russian Federation, Kazan; KazanO. D. Zinkevich
Kazan NIIEM; Kazan State Medical University
Email: info@eco-vector.com
Professor, Head of the Laboratory of Immunochemistry, Department of Infectious Diseases
Russian Federation, Kazan; Kazan