Lipid peroxidation and antioxidant system status in rheumatoid arthritis patients
- Authors: Salikhov I.G.1, Agisheva K.N.1
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Affiliations:
- Kurashov Kazan Order of the Red Banner of Labor Medical Institute
- Issue: Vol 70, No 2 (1989)
- Pages: 95-99
- Section: Articles
- URL: https://journals.rcsi.science/kazanmedj/article/view/99854
- DOI: https://doi.org/10.17816/kazmj99854
- ID: 99854
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Abstract
Recently, there has been significantly increased interest in the study of the role of free-radical lipid oxidation reactions in the development of the pathological process in rheumatoid arthritis. Immune complexes formed in this disease are a stimulus for neutrophil chemotaxis and initiation of phagocytosis reactions. The process of phagocytosis, accompanied by the release of a large number of reactive oxygen radicals, leads to damage of neutrophils themselves, release of lysosomal enzymes, degradation of collagen, hyaluronic acid and to connective tissue damage.
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##article.viewOnOriginalSite##About the authors
I. G. Salikhov
Kurashov Kazan Order of the Red Banner of Labor Medical Institute
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Kazan
K. N. Agisheva
Kurashov Kazan Order of the Red Banner of Labor Medical Institute
Email: info@eco-vector.com
Russian Federation, Kazan
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