Microvesiculas in blood of patients with acute leukoses

D M. Zubairov; Зубаиров Д. М.; I. A. Andrushko; Андрушко И. А.; L. D. Zubairova; Зубаирова Л. Д.; G. Yu. Svintenok; Свинтенок Г. Ю.; A. R. Akhmadeev; Ахмадеев А. Р.; V. N. Grigoriev; Григорьев В. Н.; Z. M. Nekhoroshkova; Нехорошкова З. М.

doi:10.17816/kazmj99849

Microvesiculas in blood of patients with acute leukoses

Authors: Zubairov DM., Andrushko I.A., Zubairova L.D., Svintenok G.Y., Akhmadeev A.R., Grigoriev V.N., Nekhoroshkova Z.M.
Issue: Vol 81, No 4 (2000)
Pages: 269-271
Section: Theoretical and clinical medicine
URL: https://journals.rcsi.science/kazanmedj/article/view/99849
DOI: https://doi.org/10.17816/kazmj99849
ID: 99849

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Abstract

The significant increase of the content of microvesiculas both in the heparinized plasma and in blood serum in patients with acute myeloblastic and acute lymphoblastic leukemia is revealed. Polychemotherapy didn’t show normalizing effect on the microvesiculation manifistation. In contrast to acute leucemia in the multiple myeloma the low level of microvesiculas is found. The possible mechanisms of invoking microvesiculas in the clinical picture of the disseminated intravascular blood coagulability syndrome in leukemia as well as in the regulation of the interaction of leukenic cell with the other blood cell and endothelium are discuss