Toxoplasmosis in clinical pathology

The significance of toxoplasmosis in clinical pathology has not yet been fully clarified. On the one hand, T. gondii is an opportunistic microorganism with low pathogenicity and evolutionarily adapted to long-term asymptomatic existence in the immune organism of its host, in particular humans; on the other hand, this parasite can activate up to life-threatening for the host if the latter has weakened or damaged immune defense mechanisms. In this context, it should be borne in mind the probability of increasing sporadic morbidity of toxoplasmosis against the background of widespread asymptomatic carriage (endemicity) due to the increasing use of corticosteroids, cytostatics, radiotherapy, leading to immunosuppression.