Modern anti-inflammatory drugs. Some aspects of the mechanism of therapeutic action and side effects

Non-steroidal anti-inflammatory drugs (NSAIDs, phlogolytics, antiphlogistics) belong to the most frequently prescribed medications in world medical practice. In combination with other drugs or individually they are used to treat rheumatic diseases, inflammatory processes in a variety of pathologies. They are widely used to relieve pain, reduce elevated body temperature. That is why the questions of development of side effects of antiphlogistics manifested by affection of different organs and systems are of particular importance. In recent years, in the literature, the issue of the interdependence of the main (anti-inflammatory) and side effects of NSAIDs, which is a direct manifestation of their pharmacological effect, is widely discussed.