Indicators of bone metabolism and bone mineral density in workers of a metallurgical plant

Abstract

The mineral density of bone tissue and phosphorus and calcium metabolism are studied by ultrasound densitometry of the calcaneus using the apparatus “Achilles+” (Lunar, USA) in 99 men working in foundry of the metallurgical alluminium works. The control group consisted of 87 healthy men of similar age. The prolonged effect of aerosols of aluminium, lead, nickel, chromium, manganese, copper is accompanied by more frequent decrease the mineral density of bone tissue, increase of incidence of osteoporosis. Workers of aluminium production are characterised by hyperphosphatemia and hyperphosphaturia resulting in insignificant decrease of parathyroid hormone secretion. The normal level of osteocalcin, alcaline phosphatase in the decreased mineral density of bone tissue shows oppression of the bone-formation process in workers.

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