Histolysates and their effect on the corresponding tissues

One year ago in the January issue of "Kazan Medical Journal" was published my report, made on November 1, 1926 to the Scientific Assembly of Physicians of the State Institute for Advanced Training of Physicians under the title: "A new method of so called "rejuvenation" of organisms". I based my work on the doctrine of "natural cellular poisons", which I had been developing for many years. According to this doctrine, dissimilation products are natural and unavoidable poisons for those cells and tissues from which they were formed. This is explained by the fact that each organ, each tissue has its own specific protein. The specificity of the latter can be easily proved by immuno-biological reactions: precipitation, complement binding, anaphylaxis, etc. At the same time, the more complex the function of the cell, the more complicated is the physicochemical structure of its protein, and the more complex are the products of vital activity and metabolism that arise here.