Functions of active chlorine transport in the membrane of skeletal muscles of mammals

Abstract

It is found that cellular volume recovery j in hypertonic mediums occurs with chlorine transport involved. The increase of osmotic pressure causes the initial dehydration of the cell, then its volume is recovered up to the initial values in these conditions. The activity of chlorine transport is under the oppressive effect of the motor nerve. Postdenervational increase of intracellular content of CI is one of the reasons of the production of new cho- linoreceptors in extrasympathetic region of the muscular membrane, that is to say where thery are absent in normal muscles. By this means there is a relationship between denerva- tional activation of chlorine transport and protein synthesis processes of cholinoreceptors.

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