Circulating immune complexes in various forms of glomerulonephritis

Circulating immune complexes are found in the blood in a large number of diseases (rheumatoid arthritis, systemic lupus erythematosus, glomerulonephritis, bacterial and viral infections). However, it should be borne in mind that their appearance is also possible in the blood serum of healthy people. The improvement of research methods and the deepening of our knowledge in the field of the nature of immune complexes revealed their contradictory nature. Along with the physiological role in the regulation of the immune response, the ability of circulating immune complexes to cause inflammatory lesions is well established [10].