About local anaphylaxis in Cold-blooded

A few months before the death of prof. IG Savchenko, at his suggestion, I began work on local anaphylaxis in summer frogs. On the issue of anaphylactic state in cold-blooded people, there is still no final conclusion. In warm-blooded animals, the anaphylactic state, i.e., increased sensitivity to the repeated introduction of a foreign protein, has been established with some clarity since the time of the classical works of Richet, who worked with poisonous proteins, and Arthus, who worked with non-toxic proteins, combining all the scattered facts that had been observed before. period (Magendi, Bering, Kretz, etc.) and by their systematic works created the doctrine of increased sensitivity to repeated administration of proteins, which Richet called anaphylaxis. Since that time, a colossal amount of work has appeared with the development of a method for obtaining anaphylaxis, the essence of anaphylaxis and the diagnostic use of the phenomena of anaphylaxis. Anaphylaxis was developed mainly on warm-blooded animals and most of them were tried, and it was found that the vast majority of animals can get anaphylactic state, with the exception of some (rat, monkey).