Thermal inactivation of tissue thromboplastin
- Authors: Zubairov D.M.1, Svintenok G.Y.1
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Affiliations:
- Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov
- Issue: Vol 64, No 1 (1983)
- Pages: 26-28
- Section: Articles
- URL: https://journals.rcsi.science/kazanmedj/article/view/85814
- DOI: https://doi.org/10.17816/kazmj85814
- ID: 85814
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Abstract
Thermal inactivation of a tissue thromboplastin is a reaction of a complex order, including, in addition to denaturation of the apoprotein, disorganization of lipid components. When heated under aerobic conditions, the oxidation of thromboplastin also contributes to its inactivation. Storage of tissue thromboplastin preparations under anaerobic conditions increases their biological stability.
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##article.viewOnOriginalSite##About the authors
D. M. Zubairov
Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov
Author for correspondence.
Email: info@eco-vector.com
Department of Biochemistry
Russian Federation, KazanG. Y. Svintenok
Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov
Email: info@eco-vector.com
Department of Biochemistry
Russian Federation, KazanReferences
Supplementary files
Supplementary Files
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1.
JATS XML
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Table 1. Dynamics of thermal inactivation of tissue thromboplastin. On the ordinate axis - thromboplastin activity in the Ig scale; on the abscissa axis - time in min.
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Fig. 2. The Lineweaver-Burke graph.
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Fig. 3. Dynamics of thermal inactivation of tissue thromboplastin in atmospheric air and nitrogen. On the ordinate axis - thromboplastin activity in the lg scale; on the abscissa axis - time in min. A is the inactivation temperature of 60°, B is the inactivation temperature of 100°.
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