Morphofunctional features of the liver in shock

Based on the modern views on shock as a process, the pathogenetic basis of which is the disorder of regulatory mechanisms, systemic disorders of the microcirculation of cell metabolism, it seems quite natural that multiple organ failure develops in shockogenic injuries. Among the organs most sensitive to extreme influences, a special place is occupied by the liver, which has become a classic object for studying the structural and metabolic manifestations of shock and its complications. At present, there is no doubt that in severe mechanical and thermal injuries, many clinical and laboratory criteria for post-aggressive states can be largely due to the severity of morphofunctional changes in the cellular composition and structural components of the liver [18, 47].