Change of zinc homeostasis in kidney diseases in children
- Authors: Makarova T.P.1,2
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Affiliations:
- Republican Center for Family, Maternity, and Childhood Protection of the Ministry of Health of the Republic of Tatarstan
- Kazan State Medical University
- Issue: Vol 82, No 4 (2001)
- Pages: 278-281
- Section: Articles
- URL: https://journals.rcsi.science/kazanmedj/article/view/83861
- DOI: https://doi.org/10.17816/kazmj83861
- ID: 83861
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Abstract
The zinc metabolism in kidney pathology in children is studied. The decrease of serum zinc level connected with its increased excretion, that is identified as deficiency of the excretory type, is revealed. The effect of the increased zinc excretion on the functional state of proximal tubules, tested by the level of aminoaciduria and phosphate reabsorption, as well as on the function of distal tubules, determined by the processes of acido- and ammoniogenesis, is established. The depressive effect of zinc on cellular and humoral immunity links as well as on phagocytic activity of neutrophiles, that is identified as dificiency of immunologic consumption, is established.
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##article.viewOnOriginalSite##About the authors
T. P. Makarova
Republican Center for Family, Maternity, and Childhood Protection of the Ministry of Health of the Republic of Tatarstan; Kazan State Medical University
Author for correspondence.
Email: info@eco-vector.com
Russian Federation
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