Adrenal lipase, its relation to poisons and clinical significance

The science of lipolytic organ enzymes has made a great step forward in the last five years. This is mainly due to Roua and his collaborators, who for the first time established a very interesting fact of selective effect of different poisons on lipase of different organs. Thus, studies by Rona, Bach and Reinicke showed that while blood serum lipase is extremely sensitive both to quinine and to atoxyl, being quite paralyzed by very small doses of these substances, liver lipase, being extremely sensitive to atoxyl, does not lose its enzymatic properties even from large doses of quinine (Rona and Pawlovic); The same is true of the kidney lipase (Rona, Retow and Schreiber) and of the pulmonary lipase to quinine.