About alkaline reserve (reserve alkalinity) in kidney disease

Abstract

The body has a complex regulatory mechanism to maintain its acid-base balance. The blood reaction, shifted somewhat to the alkaline side, fluctuates within very narrow limits. Even with increased production of acidic metabolic products, the deviation from the normal fluctuations of this individually constant value either does not occur at all or is very insignificant. A stronger deviation of blood Ph to one side or the other is incompatible with life.

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