Experiments on the cultivation of the typhoid virus

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Abstract

Starting experiments on cultivation of typhoid virus on nonpathogenic microorganisms, we settled on yeasts of Saccharomyces cerevisiae-race: M and II species (the yeasts used by Zilber, Vostroukhova and Dosser for cultivation of smallpox vaccine and typhoid virus were not yet known to us). H. Oettinger PH 7.6 broth and the same broth with 1% glucose added were used as nutrient media; otherwise, we adhered to the methodology proposed by Silber and Dosser.

About the authors

R. R. Geltzer

Territorial Microbiological Institute of TNKZ; Kazan State Medical Institute

Author for correspondence.
Email: info@eco-vector.com
Russian Federation

S. F. Nemshilov

Territorial Microbiological Institute of TNKZ; Kazan State Medical Institute

Email: info@eco-vector.com
Russian Federation

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1. JATS XML
2. Guinea pig No.142. Infected with culture 53 (I piece) of the 16th generation.

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3. Guinea pig No. 200. Infected with culture 52 (I piece) of the 16th generation.

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4. Guinea pig No.141. Infected with culture 78 (II pc.) 15th generation.

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5. Guinea pig No. 113. Infected with culture 79 (II pc.) of the 15th generation.

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6. Guinea pig No.165. Infected with culture 80 (II pc) of the 15th generation.

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7. Guinea pig No. 204. Infected with culture 81 (II pcs.) of the 15th generation.

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8. Guinea pig No. 358. Infected with culture 123 (II pc.) of the 24th generation.

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9. Guinea pig No. 263. Infected with guinea pig blood No.142.

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10. Guinea pig No. 326. Infected with guinea pig brain No. 141.

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11. Guinea pig No. 400. Infected with guinea pig brain No. 141.

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12. Guinea pig No. 347. Infected with guinea pig blood No. 165.

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13. Guinea pig No. 318. Infected with guinea pig brain No. 204.

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14. Guinea pig No. 374. Infected with guinea pig brain No. 204.

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© 1934 Geltzer R.R., Nemshilov S.F.

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