Biochemical and morphological criteria for disseminated intravascular coagulation

In the development of many diseases and pathological conditions, an important role belongs to hemocoagulation disorders, which are often realized in the form of clinical and laboratory symptoms combined into disseminated intravascular coagulation syndrome (DIC). Much fundamental research has been devoted to the study of the biochemical and morphological manifestations of this syndrome [2, 3, 5, 6], but the data presented are often contradictory, and with the advent of new theoretical concepts and methodological techniques, they require revision. Adequate laboratory diagnosis of DIC should be based on a clear understanding of its pathogenesis, without which the correct interpretation of the variable and sometimes paradoxical results of laboratory diagnostic studies is impossible.