About the role of antibodies formation in the decrease of therapeutic effect of captopril in patients with arterial hypertension
- Authors: Tikhonov V.P.1, Ilyukhin O.V.1, Yakovlev A.T.1, Statsenko M.E.1, Kirakozov D.A.1, Popova A.S.1
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Affiliations:
- Volgograd Medical Academy
- Issue: Vol 79, No 5 (1998)
- Pages: 379-381
- Section: Articles
- URL: https://journals.rcsi.science/kazanmedj/article/view/64582
- DOI: https://doi.org/10.17816/kazmj64582
- ID: 64582
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Abstract
Captopril being hapten is connected with blood serum albumin and is capable to induce antibodies elaboration. Captopril conjugate with bull serum albumin can be used as a specific diagnosticum for the hardphase immunofermental analysis. Specific immunoglobulins are one of the factors of the “escaping” effect development of the captopril hypotensive action.
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##article.viewOnOriginalSite##About the authors
V. P. Tikhonov
Volgograd Medical Academy
Author for correspondence.
Email: info@eco-vector.com
Professor, Head of the Department of Therapy, Faculty of Advanced Training for Physicians
Russian Federation, VolgogradO. V. Ilyukhin
Volgograd Medical Academy
Email: info@eco-vector.com
Advanced Training Faculty for Physicians, Department of Therapy
Russian Federation, VolgogradA. T. Yakovlev
Volgograd Medical Academy
Email: info@eco-vector.com
Advanced Training Faculty for Physicians, Department of Therapy
Russian Federation, VolgogradM. E. Statsenko
Volgograd Medical Academy
Email: info@eco-vector.com
Advanced Training Faculty for Physicians, Department of Therapy
Russian Federation, VolgogradD. A. Kirakozov
Volgograd Medical Academy
Email: info@eco-vector.com
Advanced Training Faculty for Physicians, Department of Therapy
Russian Federation, VolgogradA. S. Popova
Volgograd Medical Academy
Email: info@eco-vector.com
Advanced Training Faculty for Physicians, Department of Therapy
Russian Federation, VolgogradReferences
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