Local reaction of the nervous system in interstitial gamma therapy for eyelid cancer

The clinical picture of the general radiation response of the body and dysfunction of the central nervous system when the head area is irradiated with therapeutic doses for malignant tumors is widely presented in the literature (P, 2]. Pathological and experimental work revealed significant inflammatory and degenerative changes not only in the tissues of the brain and spinal cord, but also in the peripheral nerve trunks, nodes and, mainly, in the afferent nerve structures of the skin and mucous membrane in the irradiated area. However, the regional local reaction of the nervous system to irradiation of the eyelid region has not been studied.