Comparative evaluation of the micromethod of diphenylamine test and the reaction to sialic acids in the diagnosis of rheumatism activity

Abstract

In recent years, clinicians are increasingly using biochemical techniques to determine the activity of the rheumatic process in terms of tissue destruction. It is known that as a result of changes in connective tissue during an active rheumatic process, mucoproteins accumulate in the blood and tissues. The diphenylamine test and the reaction to sialic acids, used to detect active rheumatism, are based on the determination of mucoproteins in the blood. These reactions are based on the detection of one of the constituent parts of mucoproteins (E. G. Larsky, S. S. Mutin).

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