Method for the determination of immune complexes by reaction with polyethylene glycol

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Abstract

A study of circulating immune complexes was carried out using a reaction with polyethylene glycol. The method turned out to be simple, highly sensitive and affordable for any clinical laboratory with a photoelectric colorimeter. Analysis of the survey data of 115 healthy donors, 63 patients with rheumatoid arthritis and 16 patients with systemic lupus erythematosus made it possible to establish the level of circulating immune complexes in health and disease. The circulating immune complexes were studied in patients with rheumatism and chronic tonsillitis. To assess the results of the reaction, human aggregated gamma globulin (manufactured by Kazan NIIEM) was used.

About the authors

B. A. Molotilov

Department of Bacterial Allergy, Kazan Research Institute of Epidemiology and Microbiology

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Kazan, Russia

A. N. Mayansky

Department of Bacterial Allergy, Kazan Research Institute of Epidemiology and Microbiology

Email: info@eco-vector.com
Russian Federation, Kazan, Russia

N. D. Pozdnyak

Department of Bacterial Allergy, Kazan Research Institute of Epidemiology and Microbiology

Email: info@eco-vector.com
Russian Federation, Kazan, Russia

L. Ch. Samerkhanova

Department of Bacterial Allergy, Kazan Research Institute of Epidemiology and Microbiology

Email: info@eco-vector.com
Russian Federation, Kazan, Russia

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© 1982 Molotilov B.A., Mayansky A.N., Pozdnyak N.D., Samerkhanova L.C.

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