The case of fibrous osteodystrophy (Recklinghausen disease)

Abstract

In 1891, Recklinghausen first accurately described fibrous osteodystrophy, putting forward five main provisions that determine the essence of this disease: 1) replacement of cellular and adipose bone marrow with fibrous connective tissue; 2) resorption of bone tissue by lacunar suction; 3) metaplastic and partially osteoblastic neoplasm of osteoid and bone tissue; 4) tumor-like growths of fibrous and giant cell tissue, such as epulids, resembling giant cell sarcomas with a brown tint due to the presence of hemosiderin in the growths - "Braune tumoren" - by German authors.

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