Sensitivity of the skin of tuberculosis patients to various bacterial filtrates

The issue of mixed infection with tuberculosis has its own history. If at first the researchers Koch, Cornet, Petrushki, Vysokovich, Brauer and Peters, Maraliano, Baumgarten attached great importance to mixed infection during tuberculosis, then a number of authors, especially recently, and mainly the French school, assign it a secondary role (Besançon, Layden, Jochmann, Schrader and Manles). I. Hollo in his review article on mixed infection with tuberculosis (1930) comes to the conclusion that the question of mixed infection in general is resolved; in the cavity itself and in the respiratory tract of a tuberculosis patient, there can always be various microbes, but they behave like saprophytes or semi-parasites. It can be considered established, says Hollo, that the entire course of tuberculosis is due exclusively to the tubercle bacillus and that "there are no such forms of tuberculosis, such phases in its course, and there is not a single symptom that would depend on the action of other microbes." Even if such an impact is possible, he says, it is very insignificant and inconsistent.