To the doctrine of acute leukemia

As more and more cases of acute leukemia accumulate, it becomes clear that it can proceed in extremely different ways. Determination that it is a disease, apparently, infectious, characterized for the most part by a short course, fever, swelling of the external or internal lymph nodes, an increase in significant and extremely fast spleen, liver, hemorrhagic and blood counts and an increase in the number of leukocytes — mononuclear cells, suitable for typical cases. Between the large number of observations, not all of the listed signs are on the face, and therefore doubt may arise as to their belonging to this pathological form, although they undoubtedly belong to it only. True, there is a constant sign - a change in blood, but it is not such that it runs like a red thread from the beginning to the end of each case. Violation of the relationship between erythracytes and leukocytes sometimes develops not long before death or with known complications, and a pronounced change in blood changes its appearance to a completely different one.