А. Sibirsky. On skin changes in typhoid fever. Diss. SPB., 1900

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Abstract

In 1893 Filippovich described a special symptom in typhoid patients, which he called the palmar-plantar symptom. He observed in patients with typhoid fever, even in the absence of all the signs of this disease, on the convex parts of the palms and soles of the yellow tint, sometimes reaching the orange and saffron color. The painted places get a calloused look, even if the limbs belonged to a person who does not do physical labor. Dr. Sibirskiy set out to explain the cause of the yellow coloration of the palms and soles of II, in general, to trace the pathological and apatomical changes in the skin of these areas in typhoid fever.

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