Clinical case of multivisceral en bloc resection for locally advanced cancer of the colon hepatic flexure
- Authors: Egorov V.I.1,2, Akhmetzyanov F.S.1,2, Kaulgud H.A.2, Ruvinskiy D.M.2
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Affiliations:
- Kazan State Medical University
- Republican Clinical Oncology Dispensary
- Issue: Vol 105, No 4 (2024)
- Pages: 669-676
- Section: Clinical observations
- URL: https://journals.rcsi.science/kazanmedj/article/view/263242
- DOI: https://doi.org/10.17816/KMJ628774
- ID: 263242
Cite item
Abstract
BACKGROUND: Currently, 15–20% of colorectal cancer cases are diagnosed at the locally advanced T4b stage. Treatment of this category of patients causes significant difficulties due to the degree of prevalence and the presence of a complicated course of the disease itself.
AIM: Demonstration of a clinical case with an operation — multivisceral resection with pancreatoduodenal resection — for locally advanced cancer of the right half of the colon, as well as the oncological rationale for this operation.
MATERIAL AND METHODS: This paper describes a case of treatment of a female patient with locally advanced adenocarcinoma of the colon hepatic angle, complicated by toxic-anemic syndrome and symptoms of partial intestinal obstruction. She underwent en bloc multivisceral resection with pancreatoduodenal resection.
RESULTS: The patient was discharged on the 10th day after surgery in satisfactory condition, no complications were registered. Subsequently, adjuvant treatment was carried out: 5 courses of therapeutic polychemotherapy according to the XELOX regimen (capecitabine was received on an outpatient basis at a dose of 1500 mg 2 times a day, course 2 weeks). 12 months after surgery, progression of the disease in the form of metastases to the lungs was established, and 6 courses of bevacizumab therapy were administered. Currently the process has stabilized.
CONCLUSION: A clinical case demonstrates the possibility of R0 resection for locally advanced cancer of the colon hepatic flexure with ingrowth into the liver, pancreas, duodenum and achieving good long-term results.
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##article.viewOnOriginalSite##About the authors
Vasiliy I. Egorov
Kazan State Medical University; Republican Clinical Oncology Dispensary
Author for correspondence.
Email: drvasiliy21@gmail.com
ORCID iD: 0000-0002-6603-1390
SPIN-code: 7794-4210
MD, Cand. Csi. (Med.), Assistant, Depart. of Oncology, Radiation Diagnostics and Radiation Therapy; Oncologist, Oncology Depart. No. 11
Russian Federation, Kazan; KazanFoat Sh. Akhmetzyanov
Kazan State Medical University; Republican Clinical Oncology Dispensary
Email: akhmetzyanov@mail.ru
ORCID iD: 0000-0002-4516-1997
SPIN-code: 8908-4761
MD, Dr. Sci. (Med.), Prof., Head of Depart., Depart. of Oncology, Radiation Diagnostics and Radiation Therapy; Head, Surgical Clinic LDK2
Russian Federation, Kazan; KazanHarshal A. Kaulgud
Republican Clinical Oncology Dispensary
Email: kaulgudh@yahoo.com
ORCID iD: 0000-0002-6395-5088
SPIN-code: 1670-5876
MD, Oncologist
Russian Federation, KazanDavid M. Ruvinskiy
Republican Clinical Oncology Dispensary
Email: ruvindm@mail.ru
ORCID iD: 0000-0002-5217-7276
SPIN-code: 8998-8416
MD, Oncologist, Head of Depart., Depart. No. 11 of Oncology
Russian Federation, KazanReferences
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