Mathematical modeling of the health condition of medical workers

Aim. To create a mathematical model for identification of the relationship between the health of medical workers and the social and occupational factors, as well as a number of laboratory parameters. Methods. In an oncological hospital conducted was a cross-sectional study of the immune status of medical workers, principally the content of subpopulations of T and B lymphocytes. The model «level of health of medical workers» is based on an examination of 96 members of the medical staff who work on radiation emitting equipment, which were divided into five groups according to the nosological forms of identified diseases. The control group consisted of 98 individuals of the same medical facility, who are office workers. Results. In the individuals, who are exposed to radiation, revealed was a reduction in the functional activity of T lymphocytes, as well as an increase in the activity of natural killer cells. In the first and fifth groups (risk of tumors and diseases of the nervous system) noted was a sharp decrease in the expression of the antigens of the major histocompatibility complex system, and a reduction of the number of HLA-DR cells. In the first and second groups (risk of tumors and respiratory diseases) a decrease in the number of cells with receptors for transferrin CD71 occurred. Conclusion. The presented method of mathematical interpretation of the immunological parameters of blood will make it possible to determine the appurtenance of new study objects to a particular risk group, that is, to identify a predisposition to various diseases.

medical workers, morbidity, modeling, cluster analysis