Clinical features of enteroviral infection in pregnancy

Aim. To explore the modern clinical features of enteroviral infection in pregnancy. Methods. Comprehensive survey of 262 pregnant women was carried out. 203 patients were diagnosed with enteroviral infection, control group consisted of 59 pregnant women without enteroviral infection. All patients underwent ultrasonic fetometry, cardiotocography, placentography, ultrasonic fetometry, amniotic fluid quantitative and qualitative analysis, feto-placental, utero-placental and fetal circulation Doppler ultrasound. Results. Asymptomatic form of enteroviral infection was more frequently found in pregnant women aged 30-39 years, typical and atypical forms - in the age group of 20-29 years. The onset of menarche and the duration of the menstrual cycle were not associated with the risk for enteroviral infection. Enteroviral infection was often seen in combination with other infections and gynecological diseases. The rate of multi-infection was significantly higher in the group with typical form of entroviral infection, while atypical form of infection were mostly seen along with comorbidities. Conclusion. Immune status has a great influence on developing of clinically manifesting forms of enteroviral infection in pregnant women. Co-existence of enteroviral infection with other infectious and gynecological diseases may alter the clinical features, lead to development of atypical forms and become a significant burden to the pregnancy.

gynecological diseases, enteroviral infections, pregnancy