电邮这篇文章 Immunomorphological condition of placentas in women with repeated pregnancy losses under action of different antigens
- 作者: Zubgitskya L.1,2, Kosheleva N.1,2, Arganova O.1,2, Bespalova T.1,2, Gromiko G.1,2, Shapovalova Е.1,2, Tishkevich О.1,2
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隶属关系:
- Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- State Medical University named after acad. I.P. Pavlova
- 期: 卷 51, 编号 2 (2002)
- 页面: 43-49
- 栏目: Scientific activity
- URL: https://journals.rcsi.science/jowd/article/view/90390
- DOI: https://doi.org/10.17816/JOWD90390
- ID: 90390
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详细
The aim of the research was to investigate the pathomorphological changes in placentas of women with recurrent pregnancy losses under action of different injuring stimulus (infection, hormonal, biochemical reactions on membrans of syncytiotrophoblast and endothelium of placental vessels, actions of antiphospholipid antibodies). Identical changes was detected which connected with immune complexes (IC) formation. IC with different composition generate immunopathological processes in placental tissues. Present of antiphospholipid antibodies on placental membranes enhancing immunopathological processes, leading to dystrophic and necrotic lesions in surrounding tissues and to placental insufficiency. The outcome of this lesions is incompetent pregnancy.
Therefore IC may be the marker of placental injury and insufficiency as well as a biologic indicator of failure in reproductive system.
The treatment of threatened abortion is improve pregnancy outcomes and immunomorphological evidence.
作者简介
L. Zubgitskya
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; State Medical University named after acad. I.P. Pavlova
编辑信件的主要联系方式.
Email: info@eco-vector.com
俄罗斯联邦, Saint-Petersburg; Saint-Petersburg
N. Kosheleva
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; State Medical University named after acad. I.P. Pavlova
Email: info@eco-vector.com
俄罗斯联邦, Saint-Petersburg; Saint-Petersburg
O. Arganova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; State Medical University named after acad. I.P. Pavlova
Email: info@eco-vector.com
俄罗斯联邦, Saint-Petersburg; Saint-Petersburg
T. Bespalova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; State Medical University named after acad. I.P. Pavlova
Email: info@eco-vector.com
俄罗斯联邦, Saint-Petersburg; Saint-Petersburg
G. Gromiko
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; State Medical University named after acad. I.P. Pavlova
Email: info@eco-vector.com
俄罗斯联邦, Saint-Petersburg; Saint-Petersburg
Е. Shapovalova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; State Medical University named after acad. I.P. Pavlova
Email: info@eco-vector.com
俄罗斯联邦, Saint-Petersburg; Saint-Petersburg
О. Tishkevich
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; State Medical University named after acad. I.P. Pavlova
Email: info@eco-vector.com
俄罗斯联邦, Saint-Petersburg; Saint-Petersburg
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