Cefepim in prophylaxis of infectional complications in cesarean section in risk groups

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The efficiency and economical value of infectional surgical complications prophylaxis is considered. The risk factors included diabetes, obesity, pyelonephritis and complicated obstetrical anamnesis. The randomized trial has shown a high effectiveness of Cefepim usage administered intravenously 1.0 during CS and 8 hours later. As a standard we used Cefotaxime (2,0 gr. per day), ampicillin (4,0 qid) and gentamyein (0,24 tid). We estimated the surgical wound condition, body temperature, vaginal discharge. The effectiveness of Cefepim has made 98%. The normalization of parameters was seen up to 4-5 postoperative days.

作者简介

E. Ailamazyan

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Institute of Pharmacology, Pavlov State Medical University

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg

O. Karpov

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Institute of Pharmacology, Pavlov State Medical University

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg

M. Kutcherencko

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Institute of Pharmacology, Pavlov State Medical University

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg

A. Zaitcev

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Institute of Pharmacology, Pavlov State Medical University

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg

U. Ignatov

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Institute of Pharmacology, Pavlov State Medical University

编辑信件的主要联系方式.
Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg

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1. JATS XML
2. Graph 1. Dependence of cefepime plasma concentration on time and its relationship with MIC90.

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