Vol 52, No 1 (2003)
- Year: 2003
- Articles: 19
- URL: https://journals.rcsi.science/jowd/issue/view/4509
- DOI: https://doi.org/10.17816/JOWD.521
Full Issue
Original Research
Cholestatic hepatosis in pregnant women: pathogenesis, symptoms, therapy.
Abstract
This work studies causes, risk factors, features of the course and outcomes in 103 pregnant women with cholestatic hepatosis. The problem is significant due to the increased frequency of failure to carry the term and of perinatal pathology. Management tactics and methods for treating pregnant women with this pathology were developed. An analysis of the results indicated that including in complex therapeutic treatment of cholestatic hepatosis in pregnancy plasmapheresis and haemosorbtion increases the effectiveness of the treatment provided, improves clinico-laboratory parameters and aids to create optimal conditions for the prolongation of pregnancy and the reduction of perinatal complications.
Alternative delivery of pregnant women with operated womb
Abstract
In this article, 12-year delivery experience described of pregnant women with hem on womb after cesarean. Labored 723 women: in 465 the repeated cesarean were made, in 258 spontaneous delivery were happened. Depositions for repeated cesarean and intra-operational complications are given. Management tactics of spontaneous delivery in women in childbirth with hem on womb is described. It was decided, that delivery through natural delivery ways in women with hem on womb after cesarean in low uterine segment must be the alternative to repeated cesarean.
Vasoregulating function of vascular endothelium at physiological pregnancy and under gestosis
Abstract
In the article for the first time brought own author data, pointing to the role an endothelins, systems of oxides of nitrogen and squirrels heat shock on vasoregulation endothelium function containers, endotelium-dependent vasodilatation valued by the method. Proved role of these markers in breaking vasoregulation functions endothelium under gestosis.
Changes in thrombocytes at complicated pregnancy eph-gestosis
Abstract
One has made in women at physiological pregnancy and EPH-gestosis with the help of electron microscopy methods and microcoagulant research of functional circulating thrombocyte changes. A series of singularities of a release reaction by thrombocytes, which determine discharge of their cytoplasmatic granule contents are established. The scheme of possible development versions of a release reaction of thrombocytes is given.
Risk factors and frequency of ferrum deficiency in girls of puberty age under conditions of the far north
Abstract
According to the WHO, up to 20% of the world's population suffers from iron deficiency anemia (IDA), but this problem is most acute in obstetrics and pediatrics. It is during pregnancy and childhood that situations most often arise that lead to an iron deficiency in the body. Iron deficiency at the end of pregnancy develops in all women in a latent or explicit form, even in those cases when the initial hematopoietic parameters in the first trimester of pregnancy were normal (GA Samsygina, 2001; SI Vakhrameeva et al.; 1996). IDA, as well as latent iron deficiency, can be the cause of fetal sideropenia, as well as the cause of anemia in the postnatal period.
Use of dufastone in therapy of pregnancy loss
Abstract
The study purpose is realizing efficiency of synthetic analog of progesterone-dufastone (didrogesterone) for threatening abort therapy and dynamics evaluation of blood progesterone contents during treatment with dufastone. Dufastone use is pathogenetically proved, its high efficiency for treatment of pregnancy loss at early terms is affirmed. Dufastone application helps to protect pregnancy and has not negative influences on pregnant woman and fetus state. 93,5% of pregnancies in women with fetus loss in anamnesis were completed with deliveries.
Use of betadin for treatment of non-pregnant women with bacterialvaginosis or vaginitis
Abstract
The article presents the data on the efficiency of using betadin to treat 17 non-pregnant women who had bacterial vaginosis or vaginitis with ureaplasmas and other microorganisms in their vaginal discharge. The use of suppositoria betadin for 14 days and specific antibacterial or antimicotic therapy allowed achieve clinical recovery and elimination of ureaplasmas in 82,4% cases.
Pplication estrogens and gestogens at autoimmune ovaritis
Abstract
One studied hormonal indices (FSG, LG, prolactin, estradiol, progesterone) and anti-ovary auto anti-body contents in blood of 39% patients of reproductive age with autoimmune ovaritis. It was revealed in 18 patients the hypergonadotrope ovary insufficiency, which manifested itself as amenorrhea, in 21 patients the normogonsdotrope ovary insufficiency, which manifested itself as opsooligoamenorrhea or amenorrhea. Number of anti-ovary auto anti-bodies in blood was significantly more in studied patients than in healthy women. The statistically reliable decrease of anti-ovary auto anti-bodies happened in most patients in 6 months of estrogen and gestagen therapy. Restoration of ovary menstrual cycle happened in part of patients with normogonadotrope form of autoimmune ovaritis after such a therapy repeal. Authors associate therapeutic effect with decreasing gonadotrope ovary stimulation and with influence of estrogens and gestagens upon the immune system.
Reviews
Cytogenetical aspects of miscarriages and reproductive failures at assisted fertilization technologies
Abstract
It is known that chromosomal abnormalities are one of the most important causes of the spontaneous abortions. In this review we have considered the cytogenetical disturbances which can lead to miscarriages and embrio losses at assisted fertilization technologies. We have analyzed the structure of chromosome aberrations in spontaneous abortions and influence of the different types of alterations on the forecasting the future pregnancy outcomes. It has been considered the probability of recurrence of the pregnancy losses in patients-carriers of structural balanced chromosome rearrangements. In vitro fertilization implantation failures like as the miscarriages can depend on presence of chromosome anomalies including the occasions when the parents are the carriers of structural unbalanced rearrangements. So the kariotyping of couples, which require the assisted fertilization technologies, should be the necessary part of preliminary investigation.
Advanced methods for molecular-biological diagnostics of genital infections
Abstract
At present to diagnose infectious diseases new achievements of molecular biology are more often used equally with classic cultural methods. The article briefly presents the base of molecular-biological diagnostics of infections and the use of nucleic acids amplification with different arrangements of polimerase chain reaction including that being performed in real time. Examples of quantitative determination of DNA of microorganisms actual for obstetrics and neonatology.
jubilee
Current public health problems
Social-hygienic factors in maternal mortality
Abstract
In this article, medico-social factors of maternal mortality in St. Petersburg are presented. St. Petersburg is a city pertaining to the middle group of regions according to index on 100000 living bom infants. This material analysis affirms the high extra genital morbidity, infectious severity, specifically, high frequency of IPPP germ-carrying and unfortunate social factors: pregnancy without marriage, belonging to socially unhappy population layers, narcomania, alcoholism, refusal of medical observation and help.
HIV / AIDS in St. Petersburg and ways to provide specialized care for HIV-infected pregnant women
Abstract
The specialized assistance to HVI-infected pregnant women is organized in our city and to their infants. One performs testing pregnant women in reference to HVI infection, observation of HVI-infected pregnant women, chemoprophylaxis of perinatal HVI transmission, dispenserisation of infants born in HVI-infected mothers. Infants having any pathology are moved from maternity hospitals to suitable child's hospitals.
This work is made in close collaboration with the scientific and prophylactic center of Ministry of health protection for prophylaxis and treatment of HVI-infection in pregnant women and children.
Lectures
Intensive treatment in observing pregnant women with Rh-isoimmunization
Abstract
Diagnosis and treatment of hemolytic disease of fetus is one of the urgent problems of contemporary obstetrics. This article reveals the cause and pathophysiologic basis of its development. It shows steps in observing pregnant women with Rh-immunization, determines criteria of severity of hemolytic disease. One can find indications for intra-uterine transfusion of donor's erythrocytes.
Contemporary principles of intensive- reanimation assistance to new-born infants
Abstract
Contemporary principles of the intensive assistance to new bom infants include the maximum approximation of intensive therapy to the first minutes of infant life due to rational service organization, prophylaxis of critical states on the base of monitoring information upon processes of adaptation and desadaptation to postnatal life, elaboration of standard protocols of diagnostics and therapy of critical states in new born infants on the base of contemporary technologies and humanization of the intensive assistance.
Viewpoint
History page
Cesarean in Saint Petersburg
Abstract
Caesarean section in modern operative obstetrics belongs to the leading place. Delivery by cesarean section replaced long-term traumatic childbirth with repeated stimulation of labor and such operations as extraction of the fetus at the pelvic end, obstetric forceps, vacuum extraction of the fetus. In the Russian Federation, the frequency of caesarean section has increased 3 times in recent decades and in 1995 it was 11%. In St. Petersburg, according to the Health Committee in 1995-96. it was 12. 8%, and in 2001 it reached 15. 1%.
То history of organization of obstetrics assistance in the Russian Army
Abstract
Until now, it was believed that the first experience of using female labor in military medicine dates back to the middle of the 19th century, when during the Crimean War of 1853-1856. a detachment of sisters of mercy under the leadership of N. I. Pirogov worked in the theater of military operations. However, some documents indicate that in peacetime, female personnel in domestic military medicine began to be used much earlier.