Features of functional maturation of the central nervous system in fetuses with multiple pregnancies

The study was undertaken to detect some peculiarities of fetal «rest — activity» cycle formation in multiple pregnancy. 86 fetuses (43 twins) were observed with the following assessment of the newborns’neurological status. The «rest — activity» cycle parameters and haemodynamic indices of fetoplacental system were examined. Also there was considered the influence of IUGR and twins birth weight discordance on CNSfunctionalformation. The results showed that twins comparing with single pregnancies are characterized by the retardation of «rest — activity» cycle formation that is manifested in shortening оf the quite and prolongation оf the intermediate states, lowering of cardiac rhythm variability and motorcardial reflex. These findings substantiate the necessity of including twins into high-risk group concerning neurological disorders in the newborns. The IUGR appears an additional factor increasing this risk.