Hemodynamical parameters in functional system "motherplacenta-fetus" in women had higher levels of alpha-fetoprotein (AFP) and horionic gonadotropin (HG) in 11 trimester of pregnancy
- Authors: Gagarina A.V.1, Pavlova N.G.1, Kaicheeva T.K.1
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Affiliations:
- Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- Issue: Vol 51, No 4 (2002)
- Pages: 22-26
- Section: Current public health problems
- URL: https://journals.rcsi.science/jowd/article/view/91092
- DOI: https://doi.org/10.17816/JOWD91092
- ID: 91092
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Abstract
Haemodinamic parameters in the functional system mother-placenta-fetus in 49 women with elevated mildtrimester maternal serum AFP (>2MoM) and in 38 women with elevated maternal serum hCG (>2MoM) were studed. The control group included 32 women with normal mildtnmester serum AFP and hCG. Indexes of impedance to flow in the uterine arteries were significantly higher in patients with elevated MSAFP or MShCG comparing with women of the control group, beginning from 28 weeks of pregnancy. There was a significant association between the maternal serum AFP levels and indexes of impedance to flow in the uterine artery, umbilical artery and fetal aorta during pregnancy. In patients with abnormal (more then 95th centile) uterine arteries Resistance Index at 2024 weeks, abnormal dynamic of MSAFP and MShCC levels from 16 until 24 weeks was observed. We suppose that unexplained elevated mildtri mester maternal serum AFP and hCC сaп be associated with disturbed utero-placental circulation.
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##article.viewOnOriginalSite##About the authors
A. V. Gagarina
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Saint Petersburg
N. G. Pavlova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Russian Federation, Saint Petersburg
T. K. Kaicheeva
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Russian Federation, Saint Petersburg