The Influence of hormonal therapy on bone tissue: myths and reality

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Abstract

The paper presents a review of the current literature on the impact of estrogen, progesterone, and estrogen-progestin drugs (combined oral contraceptives, drugs for menopausal hormone therapy), thyroid, and glucocorticoid hormones on bone tissue. In this review, we discuss the pathogenetic mechanisms of the effects of various bioactive compounds on bone, and the results of domestic and foreign research.

About the authors

Maria A. Shalina

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Author for correspondence.
Email: amarus@inbox.ru

MD, PhD, the Head of the Menopause and Women’s Health Center. The Department of Endocrinology of Reproduction

Russian Federation, Saint Petersburg

Maria I. Yarmolinskaya

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: m.yarmolinskaya@gmail.com

MD, PhD, DSci (Medicine), Professor of the Russian Academy of Sciences, the Head of the Department of Endocrinology of Reproduction, the Head of the Diagnostics and Treatment of Endometriosis Center

Russian Federation, Saint Petersburg

Elena I. Abashova

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: abashova@yandex.ru

MD, PhD, Senior Researcher. The Department of Endocrinology of Reproduction

Russian Federation, Saint Petersburg

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Copyright (c) 2018 Shalina M.A., Yarmolinskaya M.I., Abashova E.I.

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