Pregnancy and delivery in patients with hepatolenticular degeneration
- Authors: Vakharlovsky V.G.1, Lagkueva F.K.2, Kusova S.O.3, Tzidaeva T.I.3
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Affiliations:
- Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- Republican medicogenetic consultation
- FUV North Ossetian State Medical Academy
- Issue: Vol 52, No 4 (2003)
- Pages: 68-71
- Section: Casuistry
- URL: https://journals.rcsi.science/jowd/article/view/89340
- DOI: https://doi.org/10.17816/JOWD89340
- ID: 89340
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Abstract
Data of pregnancy course and delivery in 3 patients with hepatolenticular degeneration (GLD) — a rare disease of autosomal recessive inheritance pattern are presented. In one case GLD was diagnosed prior pregnancy and treatment with cuprenil was continued during pregnancy. No progressive GLD clinical symptoms were observed. However pregnancy and delivery appeared to provoke GLD typical manifestations in other two patients. They have not got specific treatment with cuprenil during pregnancy as disease was diagnosed only after delivery.
Deliveries in patients with GLD were successful and the newborns were healthy. No evidence of cuprenil teratogenic effect on fetus was revealed in the first case. This GLD is not contraindication for successful pregnancy but it is necessary to use cuprenil for prevention of disease exacerbation.
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##article.viewOnOriginalSite##About the authors
V. G. Vakharlovsky
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Author for correspondence.
Email: info@eco-vector.com
Department of Obstetrics and Gynecology
Russian Federation, Saint PetersburgF. K. Lagkueva
Republican medicogenetic consultation
Email: info@eco-vector.com
Russian Federation, Vladikavkaz
S. O. Kusova
FUV North Ossetian State Medical Academy
Email: info@eco-vector.com
republican center for family planning and reproduction
Russian Federation, VladikavkazT. I. Tzidaeva
FUV North Ossetian State Medical Academy
Email: info@eco-vector.com
Department of Obstetrics and Gynecology
Russian Federation, Vladikavkaz