A comparative estimation of the results of 'natural’ and 'synthetic' estrogens application in gonadal disgenesis

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Abstract

Gonadal disgenesis concerns to the genetically caused forms of a delay of sexual development (DSD) in men. Despite of its rare appearance in a population, the large importance all over the world is given to a gonadal disgenesis problem. The results of the carried out research are the convincing the proof of an acceptability and expediency of hormonal replacement therapy assignment in patients with gonadal disgenesis with preparations containing estradiol valeratis in a combination with medroxyprogesteron without a dependence from the form of the diseases.

About the authors

E. V. Uvarova

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow

E. A. Bogdanova

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
Russian Federation, Moscow

N. S. Martysh

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
Russian Federation, Moscow

V. A. Shavaeva

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
Russian Federation, Moscow

T. V. Rudneva

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
Russian Federation, Moscow

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2. Fig. 1. Echogram of the mammary glands of patient Z., 17 years old, before (a) and 3 months later (b) after taking Divitren.

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3. Fig. 2. Dynamics of changes in hormonal status while taking ZGT in patients with dysgenesis of gonads.

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4. Fig. 3. Dynamics of uterine length and endometrial thickness (cm) as a result of changes in ZGT in patients with dysgenic gonads.

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5. Fig. 4. Changes in mammary gland echostructure against the background of ZGT in patients with gonadal dysgenesis.

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Copyright (c) 1999 Eсо-Vector



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