On some fundamental mechanical characteristics of myometrium

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Abstract

Each contractile element in muscular wall of uterus, having between itself direct mechanical relationship and spot of fixation, possesses a spontaneous contractile activity, which at isometrical mode of shortenning alike on temporary and power parameters. Functional homogeneity bounds between contractile elements, is ensured as myocites receptors characteristics, so that mechanical characteristics of connective tissue framework miometrium. To extended the optimum sprained contractile element myometrium it is necessary to apply the power 4 times greater, than the capable to develop any contractile element of myometrium during spontaneous or stimulated phasic isometric reduction.

About the authors

G. A. Savitsky

Ott Scientific Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, St. Petersburg

A. G. Savitsky

Ott Scientific Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
Russian Federation, St. Petersburg

References

Supplementary files

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2. Fig. 1. The response of the isolated myometrial strip to the pre-stretch pulse. During each pre-stretch pulse lasting 1.0 s, the length of the strip increased by 1.0 mm. Other explanations are in the text.

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3. Fig. 2. Dependence of the voltage magnitude of phase contraction of an isolated myometrium strip on the degree of its stretching. The upper curves are the magnitude of isometric maximum contraction at 1.51o, 2.01o, and 2.51o. Bottom - graph of the dependence of isometric maximum on the degree of tension of isolated myometrium strips.

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4. Fig. 3. Reductions of 21o myometrium strips located in one working chamber. A) - strips have no direct mechanical connection between them. B) - the strips are fixed to the ends of the beater, which provides direct mechanical connection between them. 1,2 - numbers of strips and synchronous recording of their activity on one recorder tape, 3 - bottom of the working chamber, 4 - dielectric beaker.

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5. Fig. 4. Scheme of the setup for studying mechanical activity of two myometrium strips, having a direct mechanical connection between them, but placed in different, not connected, working chambers: 1) frame of the setup; 2) setup for synchronous pulse stretching of both strips; 3) strain gauges; 4) beater; 5) working chamber, in which the myometrium strip is located.

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6. Fig. 5. Results of recording the synchronous contractile activity of two myometrial strips with direct mechanical connection between them, but located in isolated working chambers. (Explanations in the text)

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