Osteoprotegerin and its ligands for regulating the osteal resorption: experimental and clinical application aspects under estrogen deficiency conditions
- Authors: Yureneva S.V.1
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Affiliations:
- Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences
- Issue: Vol 53, No 1 (2004)
- Pages: 107-110
- Section: Reviews
- URL: https://journals.rcsi.science/jowd/article/view/87168
- DOI: https://doi.org/10.17816/JOWD87168
- ID: 87168
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Abstract
Modem conceptions concerning the role of OPG-RANK-RANKL system in a local paracrinic mechanism of the regulation of osteoclastogenesis and osteal resorption processes are presented in this article. Here, results of the first clinical researches of prognostic signification of ORG determinations for estimating disruption manifestations in osteal metabolism under estrogen deficiency conditions as well as data on the OPG use as an anti-resorbable agent at the treatment of post-menopausal osteoporosis.
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##article.viewOnOriginalSite##About the authors
S. V. Yureneva
Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences
Author for correspondence.
Email: info@eco-vector.com
department of gynecological endocrinology, obstetrician-gynecologist, endocrinologist
Russian Federation, Moscow